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Compare/R50.84 vs T80.49XS

R50.84 vs T80.49XS

R50.84 (Febrile nonhemolytic transfusion reaction) compared with T80.49XS (Other Rh incompatibility reaction due to transfusion of blood or blood products, sequela), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. T80.49XS carries an Excludes2 note covering R50.84: “febrile nonhemolytic transfusion reaction (R50.84)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

R50.84Febrile nonhemolytic transfusion reactionT80.49XSOther Rh incompatibility reaction due to transfusion of blood or blood products, sequela
Billing statusBillableBillable
ClassificationR00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionFebrile nonhemolytic transfusion reaction is a billable ICD-10-CM diagnosis code (R50.84).Other Rh incompatibility reaction due to transfusion of blood or blood products, sequela is a billable ICD-10-CM diagnosis code (T80.49S).
7th characterThe appropriate 7th character is to be added to each code from category T80
Includes
FNHTR
Posttransfusion fever
complications following perfusion
Delayed serologic transfusion reaction (DSTR) from Rh incompatibility
Other reaction to Rh incompatible blood transfusion
Use additional code
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources