R85.61 vs R85.81
R85.61 (Abnormal cytologic smear of anus) compared with R85.81 (Anal high risk human papillomavirus (HPV) DNA test positive), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. R85.61 carries an Excludes2 note covering R85.81: “anal high risk human papillomavirus (HPV) DNA test positive (R85.81)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| R85.61Abnormal cytologic smear of anus | R85.81Anal high risk human papillomavirus (HPV) DNA test positive | |
|---|---|---|
| Billing status | Non-billable header | Billable |
| Classification | R00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99) | R00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99) |
| Definition | Abnormal cytologic smear of anus is a non-billable ICD-10-CM category code (R85.61). | Anal high risk human papillomavirus (HPV) DNA test positive is a billable ICD-10-CM diagnosis code (R85.81). |
| Includes | abnormal findings in peritoneal fluid abnormal findings in saliva | abnormal findings in peritoneal fluid abnormal findings in saliva |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources