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R87.622 vs R87.811

R87.622 (Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)) compared with R87.811 (Vaginal high risk human papillomavirus (HPV) DNA test positive), from the official CMS tabular data.

Summary

These codes can be reported together when both conditions are documented, because R87.622 lists R87.811 under Excludes2, which marks them as distinct conditions.

Official rule
What is different?

The conditions named.R87.622 is “Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)”; R87.811 is “Vaginal high risk human papillomavirus (HPV) DNA test positive”.

Registry fact

Can these codes be reported together?

Yes, when both are documented.R87.622 lists R87.811 under Excludes2: “vaginal high risk human papillomavirus (HPV) DNA test positive (R87.811)”. Excludes2 marks distinct conditions that may both be reported when both are documented.

Official ruleGuide: Excludes1 vs Excludes2

Is there an Excludes1 relationship?

None.Neither entry carries an Excludes1 note that names the other code. R87.622 carries 10 Excludes1 notes and R87.811 carries 4 Excludes1 notes covering other codes; the side-by-side table quotes them.

Official rule

Is there an Excludes2 relationship?

Yes.R87.622’s tabular entry: “vaginal high risk human papillomavirus (HPV) DNA test positive (R87.811)”. The note covers R87.811.

Official ruleGuide: Excludes1 vs Excludes2

Is one more specific?

No.Neither is a subdivision of the other, and neither title is the unspecified form; they describe different conditions within category R87.

Registry fact

Is one a parent or header code?

No.Both are billable codes, and neither contains the other.

Registry fact

Are there sequencing instructions?

None.Neither entry carries a Code First or Use Additional Code note that names the other.

Official rule

Are there other coding relationships?

None found.No laterality, encounter-phase, Table of Neoplasms, Table of Drugs and Chemicals, or history-versus-active-disease relationship links these codes.

MedCoder-derived

Official rule: a tabular instructional note or a section of the ICD-10-CM Official Guidelines, quoted as published. Registry fact: the codes’ own published attributes (titles, billable status, position in the hierarchy, code set). MedCoder-derived: a reading MedCoder computes from those facts; it is not itself a rule. How to read the labels

Can these codes be reported together?

Informational

Excludes2 relationship

R87.622
Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)
↔
R87.811
Vaginal high risk human papillomavirus (HPV) DNA test positive

What we found

Yes, when both are documented.R87.622 carries an Excludes2 note covering R87.811: “vaginal high risk human papillomavirus (HPV) DNA test positive (R87.811)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

What to review

Report both only when the documentation supports both conditions; otherwise report the one documented.

Guide: Excludes1 vs Excludes2Check these on a claim

Why it matters

An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.

Source / rule

CMS ICD-10-CM tabular instructional notes

Official guidance behind these answers

  • Section I.A.12.b — Excludes2 · applies to: Excludes2

    A type 2 Excludes note represents “Not included here.” An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.

    ICD-10-CM Official Guidelines FY2026

Quoted from the ICD-10-CM Official Guidelines for Coding and Reporting in effect for the release shown. The tabular notes above are the code-level instruction; these sections are the convention that says how such a note is applied. Source document (CMS PDF) · Release and checksum

Side by side

R87.622Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)R87.811Vaginal high risk human papillomavirus (HPV) DNA test positive
Billing statusBillableBillable
ClassificationR00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99)R00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99)
DefinitionLow grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL) is a billable ICD-10-CM diagnosis code (R87.622).Vaginal high risk human papillomavirus (HPV) DNA test positive is a billable ICD-10-CM diagnosis code (R87.811).
Includes
abnormal findings in secretion and smears from cervix uteri
abnormal findings in secretion and smears from vagina
abnormal findings in secretion and smears from vulva
abnormal findings in secretion and smears from cervix uteri
abnormal findings in secretion and smears from vagina
abnormal findings in secretion and smears from vulva
Excludes1
abnormal cytological findings in specimens from cervix uteri (R87.61-)
abnormal cytological findings in specimens from other female genital organs (R87.69)
carcinoma in situ of vagina (histologically confirmed) (D07.2)
vaginal intraepithelial neoplasia I [VAIN I] (N89.0)
vaginal intraepithelial neoplasia II [VAIN II] (N89.1)
vaginal intraepithelial neoplasia III [VAIN III] (D07.2)
dysplasia (mild) (moderate) of vagina (histologically confirmed) (N89.-)
severe dysplasia of vagina (histologically confirmed) (D07.2)
abnormal findings on antenatal screening of mother (O28.-)
diagnostic abnormal findings classified elsewhere - see Alphabetical Index
anogenital warts due to human papillomavirus (HPV) (A63.0)
condyloma acuminatum (A63.0)
abnormal findings on antenatal screening of mother (O28.-)
diagnostic abnormal findings classified elsewhere - see Alphabetical Index
Excludes2
vaginal high risk human papillomavirus (HPV) DNA test positive (R87.811)
vaginal low risk human papillomavirus (HPV) DNA test positive (R87.821)
abnormal findings on examination of blood, without diagnosis (R70-R79)
abnormal findings on examination of urine, without diagnosis (R80-R82)
abnormal tumor markers (R97.-)
abnormal findings on examination of blood, without diagnosis (R70-R79)
abnormal findings on examination of urine, without diagnosis (R80-R82)
abnormal tumor markers (R97.-)
Use additional code
code to identify acquired absence of uterus and cervix, if applicable (Z90.71-)
—

Notes are the code’s own tabular entry, quoted as published. A note that names the other code is the one the verdict above rests on.

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Derived from the official CMS ICD-10-CM tabular data (FY2027). A coding-rule comparison, not billing advice: payer-specific edits and medical-necessity policy are outside its scope. All data sources