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R89.5 vs Z22

R89.5 (Abnormal microbiological findings in specimens from other organs, systems and tissues) compared with Z22 (Carrier of infectious disease), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. R89.5 carries an Excludes1 note covering Z22: “colonization status (Z22.-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

R89.5Abnormal microbiological findings in specimens from other organs, systems and tissuesZ22Carrier of infectious disease
Billing statusBillableNon-billable header

Report instead: Z22.0, Z22.1, Z22.2, Z22.31, Z22.321

ClassificationR00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99)Z00-Z99 — Factors Influencing Health Status and Contact with Health Services (Z00-Z99)
DefinitionAbnormal microbiological findings in specimens from other organs, systems and tissues is a billable ICD-10-CM diagnosis code (R89.5).Carrier of infectious disease is a non-billable ICD-10-CM category code (Z22).
Includes
abnormal findings in nipple discharge
abnormal findings in synovial fluid
abnormal findings in wound secretions
Positive culture findings in specimens from other organs, systems and tissues
colonization status
suspected carrier

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources