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S80.221S vs S80.222S

S80.221S (Blister (nonthermal), right knee, sequela) compared with S80.222S (Blister (nonthermal), left knee, sequela), from the official CMS tabular data. S80.221S and S80.222S code the same condition on opposite sides.

Relationship

Review

Laterality relationship

S80.221S
Right
Blister (nonthermal), right knee, sequela
S80.222S
Left
Blister (nonthermal), left knee, sequela

Same condition; these differ only in which side is documented.

These codes share a category and title and differ only in the side affected. The documentation decides which applies, and a bilateral code is reported only where the code set provides one.

Source: ICD-10-CM tabular list (laterality variant derived from the code title)

Can these codes be reported together?

Same condition, opposite side. S80.221S and S80.222S name the same condition on opposite sides of the body.

Same category and title, differing only in which side is affected — the documentation decides which one applies, and a bilateral code is reported only where the code set provides one.

Side by side

S80.221SBlister (nonthermal), right knee, sequelaS80.222SBlister (nonthermal), left knee, sequela
Billing statusBillableBillable
ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionBlister (nonthermal), right knee, sequela is a billable ICD-10-CM diagnosis code (S80.221S).Blister (nonthermal), left knee, sequela is a billable ICD-10-CM diagnosis code (S80.222S).
7th characterThe appropriate 7th character is to be added to each code from category S80The appropriate 7th character is to be added to each code from category S80

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources