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Compare/T36 vs T49.5

T36 vs T49.5

T36 (Poisoning by, adverse effect of and underdosing of systemic antibiotics) compared with T49.5 (Poisoning by, adverse effect of and underdosing of ophthalmological drugs and preparations), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. T36 carries an Excludes1 note covering T49.5: “topically used antibiotic for eye (T49.5)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

T36Poisoning by, adverse effect of and underdosing of systemic antibioticsT49.5Poisoning by, adverse effect of and underdosing of ophthalmological drugs and preparations
Billing statusNon-billable header

Report instead: T36.0X1A, T36.0X1D, T36.0X1S, T36.0X2A, T36.0X2D

Non-billable header

Report instead: T49.5X1A, T49.5X1D, T49.5X1S, T49.5X2A, T49.5X2D

ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionPoisoning by, adverse effect of and underdosing of systemic antibiotics is a non-billable ICD-10-CM category code (T36).Poisoning by, adverse effect of and underdosing of ophthalmological drugs and preparations is a non-billable ICD-10-CM category code (T49.5).
7th characterThe appropriate 7th character is to be added to each code from category T36The appropriate 7th character is to be added to each code from category T49
Includes
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
poisoning by, adverse effect of and underdosing of glucocorticoids, topically used
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
Use additional code
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
Code first
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources