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T36 vs T80.82

T36 (Poisoning by, adverse effect of and underdosing of systemic antibiotics) compared with T80.82 (Complication of immune effector cellular therapy), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Relationship

Sequencing

Additional-code relationship

T80.82
Complication of immune effector cellular therapy
→
T36
Poisoning by, adverse effect of and underdosing of systemic antibiotics

Add a secondary code when documented.

“code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”

A "Use additional code" note means a secondary code should follow this one to fully describe the condition when the documentation supports it.

Source: CMS ICD-10-CM tabular instructional notes

Informational

Excludes2 relationship

T80.82
Complication of immune effector cellular therapy
↔
T36
Poisoning by, adverse effect of and underdosing of systemic antibiotics

Distinct conditions — both may be reported.

“poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”

An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.

Source: CMS ICD-10-CM tabular instructional notes

Can these codes be reported together?

Yes, when both are documented. T80.82 carries an Excludes2 note covering T36: “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Sequencing on the claim

1stT80.82  then  T36

T80.82 carries a Use Additional Code instruction covering T36: “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”

Side by side

T36Poisoning by, adverse effect of and underdosing of systemic antibioticsT80.82Complication of immune effector cellular therapy
Billing statusNon-billable header

Report instead: T36.0X1A, T36.0X1D, T36.0X1S, T36.0X2A, T36.0X2D

Non-billable header
ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionPoisoning by, adverse effect of and underdosing of systemic antibiotics is a non-billable ICD-10-CM category code (T36).Complication of immune effector cellular therapy is a non-billable ICD-10-CM category code (T80.82).
7th characterThe appropriate 7th character is to be added to each code from category T36The appropriate 7th character is to be added to each code from category T80
Includes
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
complications following perfusion
Complication of chimeric antigen receptor (CAR-T) cell therapy
Complication of IEC therapy
Use additional code
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
code to identify the specific complication, such as:
cytokine release syndrome (D89.83-)
immune effector cell-associated neurotoxicity syndrome (G92.0-)
Code first
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)
—
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Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources