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Compare/T40.5X1 vs T41.3

T40.5X1 vs T41.3

T40.5X1 (Poisoning by cocaine, accidental (unintentional)) compared with T41.3 (Poisoning by, adverse effect of and underdosing of local anesthetics), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. T41.3 carries an Excludes1 note covering T40.5X1: “cocaine (T40.5-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Yes, when both are documented. T41.3 carries an Excludes2 note covering T40.5X1: “poisoning by cocaine used as a central nervous system stimulant (T40.5X1-T40.5X4)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

T40.5X1Poisoning by cocaine, accidental (unintentional)T41.3Poisoning by, adverse effect of and underdosing of local anesthetics
Billing statusNon-billable header

Report instead: T40.5X1A, T40.5X1D, T40.5X1S

Non-billable header

Report instead: T41.3X1A, T41.3X1D, T41.3X1S, T41.3X2A, T41.3X2D

ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionPoisoning by cocaine, accidental (unintentional) is a non-billable ICD-10-CM category code (T40.5X1).Poisoning by, adverse effect of and underdosing of local anesthetics is a non-billable ICD-10-CM category code (T41.3).
7th characterThe appropriate 7th character is to be added to each code from category T40The appropriate 7th character is to be added to each code from category T41
Includes
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Use additional code
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
Code first
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources