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T42.5X5A vs T42.5X5S

T42.5X5A (Adverse effect of mixed antiepileptics, initial encounter) compared with T42.5X5S (Adverse effect of mixed antiepileptics, sequela), from the official CMS tabular data. T42.5X5A and T42.5X5S code the same injury at a different phase of treatment.

Relationship

Review

Encounter relationship

T42.5X5A
Initial encounter
Adverse effect of mixed antiepileptics, initial encounter
T42.5X5S
Sequela
Adverse effect of mixed antiepileptics, sequela

Same underlying diagnosis, different encounter phase.

The 7th character records the phase of care for the encounter being coded, so a single encounter takes one of these characters, not several. Review whether both phases belong on the same episode of care.

Source: ICD-10-CM Official Guidelines, Section I.C.19.a

Can these codes be reported together?

Same injury, other encounter phase. T42.5X5A and T42.5X5S code the same injury at a different phase of treatment, set by the 7th character.

The 7th character records the type of care given at the encounter being coded (ICD-10-CM Official Guidelines, Section I.C.19.a), so one encounter takes one of these, not both.

Side by side

T42.5X5AAdverse effect of mixed antiepileptics, initial encounterT42.5X5SAdverse effect of mixed antiepileptics, sequela
Billing statusBillableBillable
ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionAdverse effect of mixed antiepileptics, initial encounter is a billable ICD-10-CM diagnosis code (T42.5X5A).Adverse effect of mixed antiepileptics, sequela is a billable ICD-10-CM diagnosis code (T42.5X5S).
7th characterThe appropriate 7th character is to be added to each code from category T42The appropriate 7th character is to be added to each code from category T42
Includes
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Use additional code
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
Code first
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources