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T43.224 vs T43.226

T43.224 (Poisoning by selective serotonin reuptake inhibitors, undetermined) compared with T43.226 (Underdosing of selective serotonin reuptake inhibitors), from the official CMS tabular data. T43.224 and T43.226 code the same substance (Citalopram) with a different intent.

Relationship

Informational

Drug table relationship

T43.224
Poisoning by selective serotonin reuptake inhibitors, undetermined
T43.226
Underdosing of selective serotonin reuptake inhibitors

Same substance, different circumstance of exposure.

Same substance — underdosing (Citalopram)

Accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — exactly one applies to a given encounter.

Source: CMS Table of Drugs and Chemicals

Can these codes be reported together?

Same substance, different intent. T43.224 and T43.226 code the same substance (Citalopram) with a different circumstance of exposure.

From the CMS Table of Drugs and Chemicals: accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — only one of them applies to a given encounter.

Side by side

T43.224Poisoning by selective serotonin reuptake inhibitors, undeterminedT43.226Underdosing of selective serotonin reuptake inhibitors
Billing statusNon-billable headerNon-billable header
ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionPoisoning by selective serotonin reuptake inhibitors, undetermined is a non-billable ICD-10-CM category code (T43.224).Underdosing of selective serotonin reuptake inhibitors is a non-billable ICD-10-CM category code (T43.226).
7th characterThe appropriate 7th character is to be added to each code from category T43The appropriate 7th character is to be added to each code from category T43
Includes
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Use additional code
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
Code first
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources