T43.592 vs T43.595

T43.592 (Poisoning by other antipsychotics and neuroleptics, intentional self-harm) compared with T43.595 (Adverse effect of other antipsychotics and neuroleptics), from the official CMS tabular data. T43.592 and T43.595 code the same substance (Aminophenylpyridone) with a different intent.

Relationship

Informational

Drug table relationship

T43.592

Poisoning by other antipsychotics and neuroleptics, intentional self-harm

↔

T43.595

Adverse effect of other antipsychotics and neuroleptics

Same substance, different circumstance of exposure.

Same substance — adverse effect (Aminophenylpyridone)

Accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — exactly one applies to a given encounter.

Source: CMS Table of Drugs and Chemicals

Can these codes be reported together?

Same substance, different intent. T43.592 and T43.595 code the same substance (Aminophenylpyridone) with a different circumstance of exposure.

From the CMS Table of Drugs and Chemicals: accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — only one of them applies to a given encounter.

Side by side

	T43.592Poisoning by other antipsychotics and neuroleptics, intentional self-harm	T43.595Adverse effect of other antipsychotics and neuroleptics
Billing status	Non-billable header	Non-billable header
Classification	S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)	S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
Definition	Poisoning by other antipsychotics and neuroleptics, intentional self-harm is a non-billable ICD-10-CM category code (T43.592).	Adverse effect of other antipsychotics and neuroleptics is a non-billable ICD-10-CM category code (T43.595).
7th character	The appropriate 7th character is to be added to each code from category T43	The appropriate 7th character is to be added to each code from category T43
Includes	adverse effect of correct substance properly administered poisoning by overdose of substance poisoning by wrong substance given or taken in error underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed	adverse effect of correct substance properly administered poisoning by overdose of substance poisoning by wrong substance given or taken in error underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Use additional code	code(s) to specify: manifestations of poisoning underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)	code(s) to specify: manifestations of poisoning underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
Code first	, for adverse effects, the nature of the adverse effect, such as: adverse effect NOS (T88.7)	, for adverse effects, the nature of the adverse effect, such as: adverse effect NOS (T88.7)

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Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources