T45.AX2 vs T45.AX4
T45.AX2 (Poisoning by immune checkpoint inhibitors and immunostimulant drugs, intentional self-harm) compared with T45.AX4 (Poisoning by immune checkpoint inhibitors and immunostimulant drugs, undetermined), from the official CMS tabular data. T45.AX2 and T45.AX4 code the same substance (Immunostimulant) with a different intent.
Can these codes be reported together?
Same substance, different intent. T45.AX2 and T45.AX4 code the same substance (Immunostimulant) with a different circumstance of exposure.
From the CMS Table of Drugs and Chemicals: accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — only one of them applies to a given encounter.
Side by side
| T45.AX2Poisoning by immune checkpoint inhibitors and immunostimulant drugs, intentional self-harm | T45.AX4Poisoning by immune checkpoint inhibitors and immunostimulant drugs, undetermined | |
|---|---|---|
| Billing status | Non-billable header | Non-billable header |
| Classification | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) |
| Definition | Poisoning by immune checkpoint inhibitors and immunostimulant drugs, intentional self-harm is a non-billable ICD-10-CM category code (T45.AX2). | Poisoning by immune checkpoint inhibitors and immunostimulant drugs, undetermined is a non-billable ICD-10-CM category code (T45.AX4). |
| 7th character | The appropriate 7th character is to be added to each code from category T45 | The appropriate 7th character is to be added to each code from category T45 |
| Includes | adverse effect of correct substance properly administered poisoning by overdose of substance poisoning by wrong substance given or taken in error underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed | adverse effect of correct substance properly administered poisoning by overdose of substance poisoning by wrong substance given or taken in error underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed |
| Use additional code | code(s) to specify: manifestations of poisoning underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9) | code(s) to specify: manifestations of poisoning underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9) |
| Code first | , for adverse effects, the nature of the adverse effect, such as: adverse effect NOS (T88.7) | , for adverse effects, the nature of the adverse effect, such as: adverse effect NOS (T88.7) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources