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T46.6X2 vs T46.6X5

T46.6X2 (Poisoning by antihyperlipidemic and antiarteriosclerotic drugs, intentional self-harm) compared with T46.6X5 (Adverse effect of antihyperlipidemic and antiarteriosclerotic drugs), from the official CMS tabular data. T46.6X2 and T46.6X5 code the same substance (Acipimox) with a different intent.

Can these codes be reported together?

Same substance, different intent. T46.6X2 and T46.6X5 code the same substance (Acipimox) with a different circumstance of exposure.

From the CMS Table of Drugs and Chemicals: accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — only one of them applies to a given encounter.

Side by side

T46.6X2Poisoning by antihyperlipidemic and antiarteriosclerotic drugs, intentional self-harmT46.6X5Adverse effect of antihyperlipidemic and antiarteriosclerotic drugs
Billing statusNon-billable headerNon-billable header
ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionPoisoning by antihyperlipidemic and antiarteriosclerotic drugs, intentional self-harm is a non-billable ICD-10-CM category code (T46.6X2).Adverse effect of antihyperlipidemic and antiarteriosclerotic drugs is a non-billable ICD-10-CM category code (T46.6X5).
7th characterThe appropriate 7th character is to be added to each code from category T46The appropriate 7th character is to be added to each code from category T46
Includes
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Use additional code
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
Code first
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources