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T46.6X5 vs T46.6X6

T46.6X5 (Adverse effect of antihyperlipidemic and antiarteriosclerotic drugs) compared with T46.6X6 (Underdosing of antihyperlipidemic and antiarteriosclerotic drugs), from the official CMS tabular data. T46.6X5 and T46.6X6 code the same substance (Acipimox) with a different intent.

Can these codes be reported together?

Same substance, different intent. T46.6X5 and T46.6X6 code the same substance (Acipimox) with a different circumstance of exposure.

From the CMS Table of Drugs and Chemicals: accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — only one of them applies to a given encounter.

Side by side

T46.6X5Adverse effect of antihyperlipidemic and antiarteriosclerotic drugsT46.6X6Underdosing of antihyperlipidemic and antiarteriosclerotic drugs
Billing statusNon-billable headerNon-billable header
ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionAdverse effect of antihyperlipidemic and antiarteriosclerotic drugs is a non-billable ICD-10-CM category code (T46.6X5).Underdosing of antihyperlipidemic and antiarteriosclerotic drugs is a non-billable ICD-10-CM category code (T46.6X6).
7th characterThe appropriate 7th character is to be added to each code from category T46The appropriate 7th character is to be added to each code from category T46
Includes
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Use additional code
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
Code first
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources