T47.8X5 vs T47.8X6

T47.8X5 (Adverse effect of other agents primarily affecting gastrointestinal system) compared with T47.8X6 (Underdosing of other agents primarily affecting gastrointestinal system), from the official CMS tabular data. T47.8X5 and T47.8X6 code the same substance (Algin) with a different intent. MedCoder-derived

Relationship

Informational

Drug table relationship

T47.8X5

Adverse effect of other agents primarily affecting gastrointestinal system

↔

T47.8X6

Underdosing of other agents primarily affecting gastrointestinal system

Same substance, different circumstance of exposure.

Same substance — underdosing (Algin)

Accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — exactly one applies to a given encounter.

Source: CMS Table of Drugs and Chemicals

Can these codes be reported together?

Same substance, different intent. T47.8X5 and T47.8X6 code the same substance (Algin) with a different circumstance of exposure.

From the CMS/CDC Table of Drugs and Chemicals: accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — only one of them applies to a given encounter.

Side by side

	T47.8X5Adverse effect of other agents primarily affecting gastrointestinal system	T47.8X6Underdosing of other agents primarily affecting gastrointestinal system
Billing status	Non-billable header Report instead: T47.8X5A, T47.8X5D, T47.8X5S	Non-billable header Report instead: T47.8X6A, T47.8X6D, T47.8X6S
Classification	S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)	S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
Definition	Adverse effect of other agents primarily affecting gastrointestinal system is a non-billable ICD-10-CM category code (T47.8X5).	Underdosing of other agents primarily affecting gastrointestinal system is a non-billable ICD-10-CM category code (T47.8X6).
7th character	The appropriate 7th character is to be added to each code from category T47	The appropriate 7th character is to be added to each code from category T47
Includes	adverse effect of correct substance properly administered poisoning by overdose of substance poisoning by wrong substance given or taken in error underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed	adverse effect of correct substance properly administered poisoning by overdose of substance poisoning by wrong substance given or taken in error underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Use additional code	code(s) to specify: manifestations of poisoning underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)	code(s) to specify: manifestations of poisoning underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
Code first	, for adverse effects, the nature of the adverse effect, such as: adverse effect NOS (T88.7)	, for adverse effects, the nature of the adverse effect, such as: adverse effect NOS (T88.7)

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Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources