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T48.5X3 vs T48.5X5

T48.5X3 (Poisoning by other anti-common-cold drugs, assault) compared with T48.5X5 (Adverse effect of other anti-common-cold drugs), from the official CMS tabular data. T48.5X3 and T48.5X5 code the same substance (Amidefrine) with a different intent.

Can these codes be reported together?

Same substance, different intent. T48.5X3 and T48.5X5 code the same substance (Amidefrine) with a different circumstance of exposure.

From the CMS Table of Drugs and Chemicals: accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — only one of them applies to a given encounter.

Side by side

T48.5X3Poisoning by other anti-common-cold drugs, assaultT48.5X5Adverse effect of other anti-common-cold drugs
Billing statusNon-billable headerNon-billable header
ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionPoisoning by other anti-common-cold drugs, assault is a non-billable ICD-10-CM category code (T48.5X3).Adverse effect of other anti-common-cold drugs is a non-billable ICD-10-CM category code (T48.5X5).
7th characterThe appropriate 7th character is to be added to each code from category T48The appropriate 7th character is to be added to each code from category T48
Includes
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Use additional code
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
Code first
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources