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T52.4X1 vs T52.4X2

T52.4X1 (Toxic effect of ketones, accidental (unintentional)) compared with T52.4X2 (Toxic effect of ketones, intentional self-harm), from the official CMS tabular data. T52.4X1 and T52.4X2 code the same substance (Acetone) with a different intent.

Relationship

Informational

Drug table relationship

T52.4X1
Toxic effect of ketones, accidental (unintentional)
T52.4X2
Toxic effect of ketones, intentional self-harm

Same substance, different circumstance of exposure.

Same substance — intentional self-harm (Acetone)

Accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — exactly one applies to a given encounter.

Source: CMS Table of Drugs and Chemicals

Can these codes be reported together?

Same substance, different intent. T52.4X1 and T52.4X2 code the same substance (Acetone) with a different circumstance of exposure.

From the CMS Table of Drugs and Chemicals: accidental poisoning, intentional self-harm, assault, undetermined intent, adverse effect and underdosing are mutually exclusive columns — only one of them applies to a given encounter.

Side by side

T52.4X1Toxic effect of ketones, accidental (unintentional)T52.4X2Toxic effect of ketones, intentional self-harm
Billing statusNon-billable header

Report instead: T52.4X1A, T52.4X1D, T52.4X1S

Non-billable header

Report instead: T52.4X2A, T52.4X2D, T52.4X2S

ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionToxic effect of ketones, accidental (unintentional) is a non-billable ICD-10-CM category code (T52.4X1).Toxic effect of ketones, intentional self-harm is a non-billable ICD-10-CM category code (T52.4X2).
7th characterThe appropriate 7th character is to be added to each code from category T52The appropriate 7th character is to be added to each code from category T52
Includes
Toxic effects of ketones NOS
Use additional code
code(s):
for all associated manifestations of toxic effect, such as: respiratory conditions due to external agents (J60-J70)
personal history of foreign body fully removed (Z87.821)
code(s):
for all associated manifestations of toxic effect, such as: respiratory conditions due to external agents (J60-J70)
personal history of foreign body fully removed (Z87.821)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources