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T80.30XS vs T80.A

T80.30XS (ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, sequela) compared with T80.A (Non-ABO incompatibility reaction due to transfusion of blood or blood products), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. T80.30XS carries an Excludes1 note covering T80.A: “minor blood group antigens reactions (Duffy) (E) (K) (Kell) (Kidd) (Lewis) (M) (N) (P) (S) (T80.A-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

T80.30XSABO incompatibility reaction due to transfusion of blood or blood products, unspecified, sequelaT80.ANon-ABO incompatibility reaction due to transfusion of blood or blood products
Billing statusBillableNon-billable header

Report instead: T80.A0XA, T80.A0XD, T80.A0XS, T80.A10A, T80.A10D

ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionABO incompatibility reaction due to transfusion of blood or blood products, unspecified, sequela is a billable ICD-10-CM diagnosis code (T80.30S).Non-ABO incompatibility reaction due to transfusion of blood or blood products is a non-billable ICD-10-CM category code (T80.A).
7th characterThe appropriate 7th character is to be added to each code from category T80The appropriate 7th character is to be added to each code from category T80
Includes
complications following perfusion
ABO incompatibility blood transfusion NOS
Reaction to ABO incompatibility from transfusion NOS
complications following perfusion
Reaction due to incompatibility of minor antigens (Duffy) (Kell) (Kidd) (Lewis) (M) (N) (P) (S)
Use additional code
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources