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Compare/T80.31 vs T80.91

T80.31 vs T80.91

T80.31 (ABO incompatibility with hemolytic transfusion reaction) compared with T80.91 (Hemolytic transfusion reaction, unspecified incompatibility), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. T80.91 carries an Excludes1 note covering T80.31: “ABO incompatibility with hemolytic transfusion reaction (T80.31-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

T80.31ABO incompatibility with hemolytic transfusion reactionT80.91Hemolytic transfusion reaction, unspecified incompatibility
Billing statusNon-billable header

Report instead: T80.310A, T80.310D, T80.310S, T80.311A, T80.311D

Non-billable header

Report instead: T80.910A, T80.910D, T80.910S, T80.911A, T80.911D

ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionABO incompatibility with hemolytic transfusion reaction is a non-billable ICD-10-CM category code (T80.31).Hemolytic transfusion reaction, unspecified incompatibility is a non-billable ICD-10-CM category code (T80.91).
7th characterThe appropriate 7th character is to be added to each code from category T80The appropriate 7th character is to be added to each code from category T80
Includes
complications following perfusion
complications following perfusion
Use additional code
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources