T80.5 vs T81.1
T80.5 (Anaphylactic reaction due to serum) compared with T81.1 (Postprocedural shock), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. T81.1 carries an Excludes1 note covering T80.5: “anaphylactic shock due to serum (T80.5-)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Yes, when both are documented. T81.1 carries an Excludes2 note covering T80.5: “complications following infusion, transfusion and therapeutic injection (T80.-)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| T80.5Anaphylactic reaction due to serum | T81.1Postprocedural shock | |
|---|---|---|
| Billing status | Non-billable header | Non-billable header |
| Classification | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) |
| Definition | Anaphylactic reaction due to serum is a non-billable ICD-10-CM category code (T80.5). | Postprocedural shock is a non-billable ICD-10-CM category code (T81.1). |
| 7th character | The appropriate 7th character is to be added to each code from category T80 | The appropriate 7th character is to be added to each code from category T81 |
| Includes | complications following perfusion Allergic shock due to serum Anaphylactic shock due to serum Anaphylactoid reaction due to serum | Shock during or resulting from a procedure, not elsewhere classified |
| Use additional code | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources