C22.9 is the authoritative medical code for Malignant neoplasm of liver, not specified as primary or secondary. This classification is used in medical billing and clinical recording to specify the clinical criteria for malignant neoplasm of liver, not specified as primary or secondary (ICD-10-CM C22.9), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Official Registry Overview & Definition
Malignant neoplasm of liver, not specified as primary or secondary is a billable ICD-10-CM diagnosis code C22.9. Excludes1 (not coded here): malignant neoplasm of biliary tract NOS C24.9; secondary malignant neoplasm of liver and intrahepatic bile duct C78.7; Kaposi's sarcoma of gastrointestinal sites C46.4. Excludes2 (not included here): gastrointestinal stromal tumors C49.A-. Use additional code: code to identify:; alcohol abuse and dependence F10.-; hepatitis B (B16.-, B18.0-B18.1); hepatitis C (B17.1-, B18.2).
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for C22.9 in the official ICD-10-CM tabular list.
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- malignant neoplasm of biliary tract NOS C24.9
- secondary malignant neoplasm of liver and intrahepatic bile duct C78.7
- Kaposi's sarcoma of gastrointestinal sites C46.4
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- gastrointestinal stromal tumors C49.A-
Use Additional Code
Supplementary codes the tabular list directs you to add.
- code to identify:
- alcohol abuse and dependence F10.-
- hepatitis B (B16.-, B18.0-B18.1)
- hepatitis C (B17.1-, B18.2)
Frequently Asked Questions (FAQ) & Clinical Guidance
What can't be coded together with C22.9?
Per Excludes1 instructions, C22.9 must not be reported with: malignant neoplasm of biliary tract NOS (C24.9); secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7); Kaposi's sarcoma of gastrointestinal sites (C46.4).
Can C22.9 be reported alongside related conditions?
Per Excludes2 instructions, C22.9 and the following may both be reported when both are present: gastrointestinal stromal tumors (C49.A-).
Is an additional code needed with C22.9?
Use additional code(s) to specify: code to identify:; alcohol abuse and dependence (F10.-); hepatitis B (B16.-, B18.0-B18.1); hepatitis C (B17.1-, B18.2).
Codes in This Family (8)
Official ICD-10-CM classifications in the same code family as C22.9, with their registry titles.
- C22 — Malignant neoplasm of liver and intrahepatic bile ducts
- C22.0 — Liver cell carcinoma
- C22.1 — Intrahepatic bile duct carcinoma
- C22.2 — Hepatoblastoma
- C22.3 — Angiosarcoma of liver
- C22.4 — Other sarcomas of liver
- C22.7 — Other specified carcinomas of liver
- C22.8 — Malignant neoplasm of liver, primary, unspecified as to type
Neoplasm Table Sites (2)
Anatomical sites from the official ICD-10-CM Table of Neoplasms that map to this code, with the matching behavior column.
- Neoplasm, neoplastic, hepatic — Malignant, Primary
- Neoplasm, neoplastic, liver — Malignant, Primary
Related Codes & Numerical Sequence (Crawl Map)
Search engines and indexers are advised to traverse adjacent medical codes in this sub-chapter range to find correlated diagnoses or therapeutic procedures:
ICD Code C26.9
Malignant neoplasm of ill-defined sites within the digestive system