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C81.34 ICD-10-CM Code: Lymphocyte depleted Hodgkin lymphoma, lymph nodes of axilla and upper limb

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.

  • MS-DRG 820 — LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH MCC (MDC 17)
  • MS-DRG 821 — LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH CC (MDC 17)
  • MS-DRG 822 — LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITHOUT CC/MCC (MDC 17)
  • MS-DRG 823 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITH MCC (MDC 17)
  • MS-DRG 824 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITH CC (MDC 17)
  • MS-DRG 825 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITHOUT CC/MCC (MDC 17)
  • MS-DRG 840 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH MCC (MDC 17)
  • MS-DRG 841 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH CC (MDC 17)
  • MS-DRG 842 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITHOUT CC/MCC (MDC 17)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Risk Adjustment (CMS-HCC)

Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.

  • HCC 21 — Lymphoma and Other Cancers (supersedes HCC 22, HCC 23)

Other models: CMS-HCC V22 HCC 10 · RxHCC V08 HCC 21

Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.

Official Registry Overview & Definition

Lymphocyte depleted Hodgkin lymphoma, lymph nodes of axilla and upper limb is a billable ICD-10-CM diagnosis code (C81.34).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for C81.34 in the official ICD-10-CM tabular list.

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Frequently Compared Codes

The official Excludes notes on C81.34 name these codes. Each comparison page covers when the two can — or must not — be reported together.

Change history

  • FY2017 — 2016-10-01
    Description revised
    Lymphocyte depleted classical Hodgkin lymphoma, lymph nodes of axilla and upper limb → Lymphocyte depleted Hodgkin lymphoma, lymph nodes of axilla and upper limb
    FY2017 changes
  • FY2017 — 2016-10-01
    Short description revised
    Lymphocy deplet class Hdgkn lymph, nodes of axla and upr lmb → Lymphocy deplet Hdgkn lymph, nodes of axilla and upper limb
    FY2017 changes

Verify Before Coding

  • CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.

Referenced by Other Codes

Clinical classification (AHRQ CCSR):NEO057 — Hodgkin lymphoma (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Potential MS-DRG Relationships (FY2026)

CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 80 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 9 MS-DRGs: DRG 820 (MDC 17), DRG 821 (MDC 17), DRG 822 (MDC 17), DRG 823 (MDC 17), DRG 824 (MDC 17), DRG 825 (MDC 17), DRG 840 (MDC 17), DRG 841 (MDC 17), DRG 842 (MDC 17).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Official ICD-10-CM tabular notes on other codes that name C81.34 or its code family.

3 Excludes1 notes: C26.1 (via C81.-), C76 (via C81.-), C77 (via C81.-).

1 Code First instructions: Z15.0 (via C81.-).

Contextual Map

Every relationship of C81.34 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Hierarchy

  • C00-D49 — Chapter 2: Neoplasms (C00-D49) (C00-D49) [Hierarchy]

Referenced by Excludes1 notes

  • C26.1 — Malignant neoplasm of spleen [Excludes1](via C81.-): “Hodgkin lymphoma (C81.-)” · check together
  • C76 — Malignant neoplasm of other and ill-defined sites [Excludes1](via C81.-): “malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)” · check together
  • C77 — Secondary and unspecified malignant neoplasm of lymph nodes [Excludes1](via C81.-): “malignant neoplasm of lymph nodes, specified as primary (C81-C86, C88, C96.-)” · check together

Referenced by Code First instructions

  • Z15.0 — Genetic susceptibility to malignant neoplasm [Code First](via C81.-): “, if applicable, any current malignant neoplasm (C00-C75, C81-C96)” · check together

Clinical classification (CCSR)

  • NEO057 — Hodgkin lymphoma [CCSR]

Risk adjustment (CMS-HCC)

  • HCC 21 — Lymphoma and Other Cancers [CMS-HCC]: “Lymphoma and Other Cancers — supersedes HCC 22 (Bladder, Colorectal, and Other Cancers), HCC 23 (Prostate, Breast, and Other Cancers and Tumors)”

Potential MS-DRG (9)

  • CC — Complication or Comorbidity [MS-DRG severity]: “As a secondary diagnosis this code can raise the stay's MS-DRG severity tier (CC).”
  • DRG 820 — LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH MCC [MS-DRG]: “LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH MCC (MDC 17)”
  • DRG 821 — LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH CC [MS-DRG]: “LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH CC (MDC 17)”
  • DRG 822 — LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITHOUT CC/MCC [MS-DRG]: “LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITHOUT CC/MCC (MDC 17)”
  • DRG 823 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITH MCC [MS-DRG]: “LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITH MCC (MDC 17)”
  • DRG 824 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITH CC [MS-DRG]: “LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITH CC (MDC 17)”
  • DRG 825 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITHOUT CC/MCC [MS-DRG]: “LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITHOUT CC/MCC (MDC 17)”
  • DRG 840 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH MCC [MS-DRG]: “LYMPHOMA AND NON-ACUTE LEUKEMIA WITH MCC (MDC 17)”
  • and 2 more

MDC crossing · procedures (4730)

  • MDC 17 — Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms [MDC crossing]: “Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”
  • 0016070 — Bypass Cerebral Ventricle to Nasopharynx with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Nasopharynx with Autologous Tissue Substitute, Open Approach — grouped in MDC 17, the procedure side of this code's crossing.” · check together
  • 0016071 — Bypass Cerebral Ventricle to Mastoid Sinus with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Mastoid Sinus with Autologous Tissue Substitute, Open Approach — grouped in MDC 17, the procedure side of this code's crossing.” · check together
  • 0016072 — Bypass Cerebral Ventricle to Atrium with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Atrium with Autologous Tissue Substitute, Open Approach — grouped in MDC 17, the procedure side of this code's crossing.” · check together
  • 0016073 — Bypass Cerebral Ventricle to Blood Vessel with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Blood Vessel with Autologous Tissue Substitute, Open Approach — grouped in MDC 17, the procedure side of this code's crossing.” · check together
  • 0016074 — Bypass Cerebral Ventricle to Pleural Cavity with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Pleural Cavity with Autologous Tissue Substitute, Open Approach — grouped in MDC 17, the procedure side of this code's crossing.” · check together
  • and 4725 more

Nearest codes (40)

  • C81 — Hodgkin lymphoma [Sibling]
  • C81.18 — Nodular sclerosis Hodgkin lymphoma, lymph nodes of multiple sites [Sibling]
  • C81.19 — Nodular sclerosis Hodgkin lymphoma, extranodal and solid organ sites [Sibling]
  • C81.1A — Nodular sclerosis Hodgkin lymphoma, in remission [Sibling]
  • C81.2 — Mixed cellularity Hodgkin lymphoma [Sibling]
  • C81.20 — Mixed cellularity Hodgkin lymphoma, unspecified site [Sibling]
  • C81.21 — Mixed cellularity Hodgkin lymphoma, lymph nodes of head, face, and neck [Sibling]
  • C81.22 — Mixed cellularity Hodgkin lymphoma, intrathoracic lymph nodes [Sibling]
  • and 32 more

Change history (2)

  • FY2017 — Description revised [Change history]
  • and 1 more

Nearest Codes in This Family

Official ICD-10-CM classifications closest to C81.34 in its code family, with their registry titles.

  • C81.3 — Lymphocyte depleted Hodgkin lymphoma
  • C81.30 — Lymphocyte depleted Hodgkin lymphoma, unspecified site
  • C81.31 — Lymphocyte depleted Hodgkin lymphoma, lymph nodes of head, face, and neck
  • C81.32 — Lymphocyte depleted Hodgkin lymphoma, intrathoracic lymph nodes
  • C81.33 — Lymphocyte depleted Hodgkin lymphoma, intra-abdominal lymph nodes
  • C81.35 — Lymphocyte depleted Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
  • C81.36 — Lymphocyte depleted Hodgkin lymphoma, intrapelvic lymph nodes
  • C81.37 — Lymphocyte depleted Hodgkin lymphoma, spleen
  • C81.38 — Lymphocyte depleted Hodgkin lymphoma, lymph nodes of multiple sites
  • C81.39 — Lymphocyte depleted Hodgkin lymphoma, extranodal and solid organ sites

View all codes in the C81 family