E09.354 ICD-10-CM Code: Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment
Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.
Coding at a Glance
- 7th character
- Required — see the character table on this page
- Tabular directives
- 8 Excludes1 · 6 use-additional codes · 1 code-first instruction
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for E09.354 in the official ICD-10-CM tabular list, quoted as published.
Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025
Notes without a marker are published on E09.354 itself; “inherited from” names the category or block whose note applies here.
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- diabetes mellitus due to underlying condition (E08.-) Compare E09.354 vs E08 →
- gestational diabetes (O24.4-) Compare E09.354 vs O24.4 →
- neonatal diabetes mellitus (P70.2) Compare E09.354 vs P70.2 →
- postpancreatectomy diabetes mellitus (E13.-) Compare E09.354 vs E13 →
- postprocedural diabetes mellitus (E13.-) Compare E09.354 vs E13 →
- secondary diabetes mellitus NEC (E13.-) Compare E09.354 vs E13 →
- type 1 diabetes mellitus (E10.-) Compare E09.354 vs E10 →
- type 2 diabetes mellitus (E11.-) Compare E09.354 vs E11 →
Source: inherited from E09
Code First
Underlying conditions that must be sequenced before this code.
- poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)
Source: inherited from E09
Use Additional Code
Supplementary codes the tabular list directs you to add.
- Use additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- Use additional code to identify control using:
- injectable non-insulin antidiabetic drugs (Z79.85)
- insulin (Z79.4)
- oral antidiabetic drugs (Z79.84)
- oral hypoglycemic drugs (Z79.84)
Source: inherited from E09
7th Character Guide
"One of the following 7th characters is to be assigned to codes in subcategory E09.35 to designate laterality of the disease:"
- 1 — right eye
- 2 — left eye
- 3 — bilateral
- 9 — unspecified eye
Variant codes in this family
E09.3541, E09.3542, E09.3543, E09.3549
Character meanings are CMS's official 7th-character extensions for this family, as carried in each variant code's official description; variant codes are registry rows. The explanation of how the encounter character is assigned is MedCoder editorial, distinct from the official content above it.
Coder workflow for E09.354
MedCoder structured workflow — derived from this code’s own official record
Before you code E09.354
- E09.354 is not reportable as written. Select the more specific code beneath it that the documentation supports. Codes are reported to the highest level of specificity the classification provides (Guidelines I.B.2).
ReviewE09.3541, E09.3542, E09.3543, E09.3549
See the relationships section · Guide: How to choose an ICD-10-CM code →
- A 7th character is required in this family. Confirm the documentation supports the character assigned — its meaning in this family is defined in the official instruction. E09.354 is not valid without one. The official 7th-character definitions for this family are quoted in the guide.
- E09.354’s title joins a condition with an associated condition or complication. Confirm each component is documented. Where the classification presumes the link through the “with” convention, only a provider statement that the conditions are unrelated defeats it. A combination code is assigned only when it fully identifies the documented conditions; a required second code for the stage, type or manifestation is still reported when the notes ask for it (Guidelines I.B.9, I.A.15).
- Confirm the documented diabetes type or cause (the E08–E13 categories are separated by it) and every documented complication or manifestation; the code is built from the type first and the complication second. Then work the category’s Use Additional Code notes for medication and control status. Type 2 is the default only when the type is not documented, and insulin or other medication use does not by itself establish the type (Guidelines I.C.4.a.2, I.C.4.a.3).
- Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with E09.354. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
Choose the right path
- Does the documentation support one of the more specific codes beneath E09.354?
Yes → Select that code and continue the checks below on its own page.
No → E09.354 cannot be reported as written; query for the specificity its subcategory needs. - Does the documentation support a condition named in E09.354’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue. - Is the underlying (etiologic) condition the Code First note names documented?
Yes → Sequence the underlying condition first, then E09.354.
No → Continue; do not add an underlying condition the record does not document. - Does the documentation support one of this family’s 7th-character values?
Yes → Assign the matching 7th character; the variant codes are in the 7th Character Guide.
No → The code is invalid without its 7th character — query for the missing element.
Consider E09.354. Then work the Use Additional Code note, and confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
- 7th-character basis
- The documented element this family’s 7th character records (see the official definitions in the 7th Character Guide).
- The associated condition or complication
- Whether the associated condition the title names is documented; the “with” convention presumes some links, and a provider statement that the conditions are unrelated defeats it (Guidelines I.A.15).
- The underlying (etiologic) condition
- Named in the Code First note; sequenced before this code when documented (Guidelines I.A.13).
- The conditions the Use Additional Code note names
- Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.
- Diabetes type or cause, each complication, and medication use
- The type is documented, not inferred from medication (Guidelines I.C.4.a.3); each documented complication takes its own combination code.
Official instructions as workflow
Excludes1 — check before selecting E09.354(8 notes)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with E09.354: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
CompareE08, O24.4, P70.2, E13, E10, E11
See the official tabular notes · Guidelines I.A.12.a
Code First — sequencing check(1 note)
Coding workflow: Check whether the underlying or etiologic condition the note names is documented. When it is, sequence it before E09.354. Do not add an underlying condition the record does not document.
See the official tabular notes · Guidelines I.A.13
Use Additional Code — after identifying E09.354(6 notes)
Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with E09.354 when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.
See the official tabular notes · Guidelines I.A.13
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: Both the condition E09.354 describes and a condition named in its Excludes1 note are documented for the same encounter.
Coding question: Can both codes be reported?
Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.
Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).
Documentation: Only one of the components this code’s title joins is documented.
Coding question: Is E09.354 supported?
Path: Review the code for the documented component on its own.
Reason: A combination code is assigned only when it fully identifies the documented conditions; otherwise the documented component takes its own code (Guidelines I.B.9).
Documentation: The underlying condition the Code First note names is documented alongside this condition.
Coding question: How are the two sequenced?
Path: Review the Code First note.
Reason: The underlying condition is sequenced first and the manifestation follows (Guidelines I.A.13).
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Indexed Clinical Terms (1)
Official source data — entries quoted as published, in the Index’s own lookup phrasing
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.
Decision Points
The directives on this code's own record, as a pre-claim checklist.
- A 7th character applies in this family. Confirm the documented encounter matches the character assigned. See the official 7th-character definitions and this code’s variants
- Sequencing: 1 Code First instruction — the underlying condition is sequenced before this code when present. See the Code First notes
- 6 Use Additional Code instructions — report the named additional code(s) when the documentation supports them. See the Use Additional Code notes
- 8 Excludes1 entries — codes named there are generally not reported together with this code (Guidelines I.A.12.a). See the Excludes1 notes
Checklist rows are derived from this code's own official directives; the wording of each check is MedCoder editorial. The official notes themselves are in the sections each row links to.
Verify Before Coding
- Not billable as written — a more specific code is required: E09.3541, E09.3542, E09.3543, E09.3549.
- Requires a 7th character. "One of the following 7th characters is to be assigned to codes in subcategory E09.35 to designate laterality of the disease:" Options: E09.3541, E09.3542, E09.3543, E09.3549
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name E09.354 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 24 Excludes1 notes across 8 chapters: E08 — Diabetes mellitus due to underlying condition (via E09.-), E10 — Type 1 diabetes mellitus (via E09.-), E11 — Type 2 diabetes mellitus (via E09.-), E13 — Other specified diabetes mellitus (via E09.-), E74 — Other disorders of carbohydrate metabolism (via E09.-), E87.2 — Acidosis (via E09.-), G54.5 — Neuralgic amyotrophy (via E09.-), G59 — Mononeuropathy in diseases classified elsewhere (via E09.-), G63 — Polyneuropathy in diseases classified elsewhere (via E09.-), G99.0 — Autonomic neuropathy in diseases classified elsewhere (via E09.-), H20.0 — Acute and subacute iridocyclitis (via E09.-), H36 — Retinal disorders in diseases classified elsewhere (via E09.3.-), I73.8 — Other specified peripheral vascular diseases (via E09.-), I79.8 — Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere (via E09.-), L92.1 — Necrobiosis lipoidica, not elsewhere classified (via E09.-), L99 — Other disorders of skin and subcutaneous tissue in diseases classified elsewhere (via E09.-), M14 — Arthropathies in other diseases classified elsewhere (via E09.-), M14.6 — Charcôt's joint (via E09.-), M90 — Osteopathies in diseases classified elsewhere (via E09.-), N08 — Glomerular disorders in diseases classified elsewhere (via E09.-), +4 more.
These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.
Referenced by 2 Excludes2 notes across 2 chapters: H35 — Other retinal disorders (via E09.-), I96 — Gangrene, not elsewhere classified (via E09.-).
These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.
Referenced by 1 Code First instruction: D84.81 — Immunodeficiency due to conditions classified elsewhere (via E09.-).
Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.
Referenced by 1 Code Also instruction: N76.82 — Fournier disease of vagina and vulva (via E09.-).
These codes suggest coding this condition alongside when both are present.
Related Codes
Same Index main term, other category
The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Diabetes, diabetic”; these codes share that main term but sit in a different category of the Tabular List.
E08.622 — Diabetes mellitus due to underlying condition with other skin ulcer (due to underlying condition, with, skin ulcer NEC), E08.628 — Diabetes mellitus due to underlying condition with other skin complications (due to underlying condition, with, skin complication NEC), E08.630 — Diabetes mellitus due to underlying condition with periodontal disease (due to underlying condition, with, periodontal disease), E08.638 — Diabetes mellitus due to underlying condition with other oral complications (due to underlying condition, with, oral complication NEC), E08.641 — Diabetes mellitus due to underlying condition with hypoglycemia with coma (due to underlying condition, with, hypoglycemia, with coma), E08.649 — Diabetes mellitus due to underlying condition with hypoglycemia without coma (due to underlying condition, with, hypoglycemia), E08.65 — Diabetes mellitus due to underlying condition with hyperglycemia (due to underlying condition, with, hyperglycemia), E08.69 — Diabetes mellitus due to underlying condition with other specified complication (due to underlying condition, with, complication, specified NEC), E08.8 — Diabetes mellitus due to underlying condition with unspecified complications (due to underlying condition, with, complication), E08.9 — Diabetes mellitus due to underlying condition without complications (due to underlying condition), E10.10 — Type 1 diabetes mellitus with ketoacidosis without coma (type 1, with, ketoacidosis), E10.11 — Type 1 diabetes mellitus with ketoacidosis with coma (type 1, with, ketoacidosis, with coma), E10.21 — Type 1 diabetes mellitus with diabetic nephropathy (type 1, with, nephropathy), E10.22 — Type 1 diabetes mellitus with diabetic chronic kidney disease (type 1, with, chronic kidney disease), E10.29 — Type 1 diabetes mellitus with other diabetic kidney complication (type 1, with, renal complication NEC), E10.311 — Type 1 diabetes mellitus with unspecified diabetic retinopathy with macular edema (type 1, with, retinopathy, with macular edema), E10.319 — Type 1 diabetes mellitus with unspecified diabetic retinopathy without macular edema (type 1, with, retinopathy), E10.321 — Type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema (type 1, with, retinopathy, nonproliferative, with macular edema), E10.329 — Type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy without macular edema (type 1, with, retinopathy, nonproliferative), E10.331 — Type 1 diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema (type 1, with, retinopathy, nonproliferative, moderate, with macular edema), +192 more
Contextual Map
Every relationship of E09.354 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run E09.354 with these 12 related codes in Claim Check
Hierarchy
- E00-E89 — Chapter 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89) (E00-E89)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E08-E13 — Diabetes mellitus[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Referenced by Excludes1 notes (24)
- E08 — Diabetes mellitus due to underlying condition[Excludes1](via E09.-): “drug or chemical induced diabetes mellitus (E09.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E10 — Type 1 diabetes mellitus[Excludes1](via E09.-): “drug or chemical induced diabetes mellitus (E09.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E11 — Type 2 diabetes mellitus[Excludes1](via E09.-): “drug or chemical induced diabetes mellitus (E09.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E13 — Other specified diabetes mellitus[Excludes1](via E09.-): “drug or chemical induced diabetes mellitus (E09.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E74 — Other disorders of carbohydrate metabolism[Excludes1](via E09.-): “diabetes mellitus (E08-E13)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E87.2 — Acidosis[Excludes1](via E09.-): “diabetic acidosis - see categories E08-E10, E11, E13 with ketoacidosis”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- G54.5 — Neuralgic amyotrophy[Excludes1](via E09.-): “neuralgic amyotrophy in diabetes mellitus (E08-E13 with .44)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- G59 — Mononeuropathy in diseases classified elsewhere[Excludes1](via E09.-): “diabetic mononeuropathy (E08-E13 with .41)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 16 more
Referenced by Excludes2 notes
- H35 — Other retinal disorders[Excludes2](via E09.-): “diabetic retinal disorders (E08.311-E08.359, E09.311-E09.359, E10.311-E10.359, E11.311-E11.359, E13.311-E13.359)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- I96 — Gangrene, not elsewhere classified[Excludes2](via E09.-): “gangrene in diabetes mellitus (E08-E13 with .52)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Code First instructions
- D84.81 — Immunodeficiency due to conditions classified elsewhere[Code First](via E09.-): “diabetes mellitus (E08-E13)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Code Also instructions
- N76.82 — Fournier disease of vagina and vulva[Code Also](via E09.-): “, if applicable, diabetes mellitus (E08-E13 with .9)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Index entries
- Diabetes, diabetic (mellitus) (sugar), due to drug or chemical, with, retinopathy, proliferative, with, combined traction retinal detachment and rhegmatogenous retinal detachment[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
Nearest codes (40)
- E09 — Drug or chemical induced diabetes mellitus[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E09.3491 — Drug or chemical induced diabetes mellitus with severe nonproliferative diabetic retinopathy without macular edema, right eye[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E09.3492 — Drug or chemical induced diabetes mellitus with severe nonproliferative diabetic retinopathy without macular edema, left eye[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E09.3493 — Drug or chemical induced diabetes mellitus with severe nonproliferative diabetic retinopathy without macular edema, bilateral[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E09.3499 — Drug or chemical induced diabetes mellitus with severe nonproliferative diabetic retinopathy without macular edema, unspecified eye[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E09.35 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E09.351 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with macular edema[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E09.3511 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with macular edema, right eye[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- and 32 more
Change history
- FY2017 — Added to the code set[Change history]— CMS release files (code change ledger) · icd10cm-fy2017
Common coding questions
Can E09.354 be billed directly?
No. E09.354 (Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
Does E09.354 require a 7th character?
Yes. One of the following 7th characters is to be assigned to codes in subcategory E09.35 to designate laterality of the disease:.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "E09.354 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/e09.354-drug-or-chemical-induced-diabetes-mellitus-with-proliferative-diabetic-retinopathy-with-combined-traction-retinal-detachment
Change history
- FY2017 — October 1, 2016Added to the code setDrug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachmentFY2017 changes
Nearest Codes in This Family
Official ICD-10-CM classifications closest to E09.354 in its code family, with their registry titles.
- E09.353 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula
- E09.3531 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula, right eye
- E09.3532 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula, left eye
- E09.3533 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula, bilateral
- E09.3539 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula, unspecified eye
- E09.3541 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, right eye
- E09.3542 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, left eye
- E09.3543 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, bilateral
- E09.3549 — Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, unspecified eye
- E09.355 — Drug or chemical induced diabetes mellitus with stable proliferative diabetic retinopathy