Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Risk Adjustment (CMS-HCC)

Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.

Other models: CMS-HCC V22 HCC 110 · RxHCC V08 HCC 225

Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.

Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.

Cystic fibrosis with pulmonary manifestations is a billable ICD-10-CM diagnosis code (E84.0).

Sequencing, inclusion, and exclusion notes published for E84.0 in the official ICD-10-CM tabular list.

Conditions the official ICD-10-CM tabular list includes under this code.

Conditions that can never be reported with this code; the two are mutually exclusive.

androgen insensitivity syndrome (E34.5-)
congenital adrenal hyperplasia (E25.0)
hemolytic anemias attributable to enzyme disorders (D55.-)
Marfan syndrome (Q87.4-)
5-alpha-reductase deficiency (E29.1)

Conditions not covered by this code, but which may be reported alongside it when both are present.

Additional codes that may be required to fully describe the encounter.

Supplementary codes the tabular list directs you to add.

Official ICD-10-CM classifications closest to E84.0 in its code family, with their registry titles.

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.