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E89.1 ICD-10-CM Code: Postprocedural hypoinsulinemia

Compare with another code for E89.1Check this code on a claim

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Official instructions
2 inclusion terms · 2 Excludes1 · 1 Excludes2 · 3 use-additional instructions · 1 code-first instruction

What these terms mean →

Billable · FY2027A valid, specific ICD-10-CM code, reportable for dates of service in FY2027.

What you need to know

Source: CMS/NCHS Official ICD-10-CM tabular notes, quoted. From the CMS/NCHS tabular list for the release in force. A note the category or block publishes applies to this code too, and is marked with where it comes from.

Code firstSequence the underlying condition before this code
  • Code first, if applicable, diabetes mellitus (postpancreatectomy) (postprocedural) (E13.-)
Use additional codeReport with this code when documented
  • Use additional code, if applicable, to identify:
  • acquired absence of pancreas (Z90.41-)
  • insulin use (Z79.4)
Excludes1Not reported with this code unless documented as unrelated
  • transient postprocedural hyperglycemia (R73.9)
  • transient postprocedural hypoglycemia (E16.2)
Excludes2from E89Not included here; may be reported together
  • intraoperative complications of endocrine system organ or structure (E36.0-, E36.1-, E36.8)
IncludesWhat this code covers
  • Postpancreatectomy hyperglycemia
  • Postsurgical hypoinsulinemia

Where it sits Source: CMS/NCHS

Under:Chapter 4: Endocrine, Nutritional and Metabolic DiseasesE89-E89 Postprocedural endocrine and metabolic complications and disorders, not elsewhere classifiedE89 Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified

Most relevant related codes MedCoder-derived

Read off the official notes above and this code’s own position in the tabular list. Which to report is a documentation question; Compare shows the two side by side.

CompareCheck ClaimView Related Codes

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v44, Appendix B.

  • MS-DRG 008 — SIMULTANEOUS PANCREAS, ISLET CELL AND KIDNEY TRANSPLANT (MDC PRE)
  • MS-DRG 010 — PANCREAS OR ISLET CELL TRANSPLANT (MDC PRE)
  • MS-DRG 019 — SIMULTANEOUS PANCREAS, ISLET CELL AND KIDNEY TRANSPLANT WITH HEMODIALYSIS (MDC PRE)
  • MS-DRG 640 — MISCELLANEOUS DISORDERS OF NUTRITION, METABOLISM, FLUIDS AND ELECTROLYTES WITH MCC (MDC 10)
  • MS-DRG 641 — MISCELLANEOUS DISORDERS OF NUTRITION, METABOLISM, FLUIDS AND ELECTROLYTES WITHOUT MCC (MDC 10)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for E89.1 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Notes without a marker are published on E89.1 itself; “inherited from” names the category or block whose note applies here.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Postpancreatectomy hyperglycemia
  • Postsurgical hypoinsulinemia

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Source: inherited from E89

Code First

Underlying conditions that must be sequenced before this code.

  • Code first, if applicable, diabetes mellitus (postpancreatectomy) (postprocedural) (E13.-)

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code, if applicable, to identify:
  • acquired absence of pancreas (Z90.41-)
  • insulin use (Z79.4)

Coder workflow for E89.1

MedCoder structured workflow — derived from this code’s own official record

Before you code E89.1

  1. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with E89.1. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

    See the official tabular notes

Choose the right path

  1. Does the documentation support a condition named in E89.1’s Excludes1 note?
    Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
    No → Continue.

    ReviewR73.9, E16.2

  2. Is the underlying (etiologic) condition the Code First note names documented?
    Yes → Sequence the underlying condition first, then E89.1.
    No → Continue; do not add an underlying condition the record does not document.

    ReviewE13

Consider E89.1. Then work the Use Additional Code note, and confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
The underlying (etiologic) condition
Named in the Code First note; sequenced before this code when documented (Guidelines I.A.13).
The conditions the Use Additional Code note names
Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.

Official instructions as workflow

  • Excludes1 — check before selecting E89.1(2 notes)

    Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with E89.1: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

    CompareR73.9, E16.2

    See the official tabular notes · Guidelines I.A.12.a

  • Excludes2 — not part of E89.1(1 note)

    Coding workflow: The conditions named in this note are not included in E89.1. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

    CompareE36.0, E36.1, E36.8

    See the official tabular notes · Guidelines I.A.12.b

  • Code First — sequencing check(1 note)

    Coding workflow: Check whether the underlying or etiologic condition the note names is documented. When it is, sequence it before E89.1. Do not add an underlying condition the record does not document.

    ReviewE13

    See the official tabular notes · Guidelines I.A.13

  • Use Additional Code — after identifying E89.1(3 notes)

    Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with E89.1 when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.

    ReviewZ90.41, Z79.4

    See the official tabular notes · Guidelines I.A.13

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: Both the condition E89.1 describes and a condition named in its Excludes1 note are documented for the same encounter.

Coding question: Can both codes be reported?

Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.

Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).

ReviewR73.9, E16.2

Documentation: The underlying condition the Code First note names is documented alongside this condition.

Coding question: How are the two sequenced?

Path: Review the Code First note.

Reason: The underlying condition is sequenced first and the manifestation follows (Guidelines I.A.13).

ReviewE13

Documentation: A condition the Use Additional Code note names is documented.

Coding question: Is a second code reported with E89.1?

Path: Review the Use Additional Code note and the code it names.

Reason: The additional code is reported when the record documents the condition; a conditional instruction applies only when its condition is met (Guidelines I.A.13).

ReviewZ90.41, Z79.4

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Don’t confuse E89.1 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of E89.1 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

  • R73.9— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of transient postprocedural hyperglycemia moves the case to R73.9; the two are not reported together unless documented as unrelated.

    Full comparison: E89.1 vs R73.9 →

  • E16.2— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of transient postprocedural hypoglycemia moves the case to E16.2; the two are not reported together unless documented as unrelated.

    Full comparison: E89.1 vs E16.2 →

  • E36.0— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of intraoperative complications of endocrine system organ or structure adds E36.0; it is not part of this code and both may be reported when both are documented.

    Full comparison: E89.1 vs E36.0 →

  • E36.1— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of intraoperative complications of endocrine system organ or structure adds E36.1; it is not part of this code and both may be reported when both are documented.

    Full comparison: E89.1 vs E36.1 →

  • E36.8— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of intraoperative complications of endocrine system organ or structure adds E36.8; it is not part of this code and both may be reported when both are documented.

    Full comparison: E89.1 vs E36.8 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Coding context

Guidelines, coding notes, decision aids, relationships (with MS-DRG and CCSR classification), hierarchy, HCC, coverage and the context map: what a coder reaches for after the core. Each section names whether it is official source data, a MedCoder-derived relationship or MedCoder editorial.

Code Overview

Postprocedural hypoinsulinemia is a billable ICD-10-CM diagnosis code (E89.1).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Official Coding Guidelines

Official source data — quoted verbatim from the CMS/NCHS Official Guidelines

Verbatim excerpts from the ICD-10-CM Official Guidelines for Coding and Reporting (CMS/NCHS) that govern this code.

Chapter 4: Endocrine, Nutritional, and Metabolic Diseases (E00 -E89)

(i) Secondary diabetes mellitus due to pancreatectomy For postpancreatectomy diabetes mellitus (lack of insulin due to the surgical removal of all or part of the pancreas), assign code E89.1, Postprocedural hypoinsulinemia. Assign a code from category E13 as the principal or first- listed diagnosis and a code from subcategory Z90.41, Acquired absence of pancreas, as an additional code. (ii) Secondary diabetes due to drugs Secondary diabetes may be caused by an adverse effect of correctly administered medications, poisoning or sequela of poisoning. See section I.C.19.e. for coding of adverse effects and poisoning, and section I.C.20 for external cause code reporting.

Decision Points

The directives on this code's own record, as a pre-claim checklist.

  1. Sequencing: 1 Code First instruction — the underlying condition is sequenced before this code when present. See the Code First notes
  2. 3 Use Additional Code instructions — report the named additional code(s) when the documentation supports them. See the Use Additional Code notes
  3. 2 Excludes1 entries — codes named there are generally not reported together with this code (Guidelines I.A.12.a). See the Excludes1 notes
  4. 1 Excludes2 entry — those conditions are not part of this code and may be reported additionally when documented. See the Excludes2 notes

Checklist rows are derived from this code's own official directives; the wording of each check is MedCoder editorial. The official notes themselves are in the sections each row links to.

Verify Before Coding

  • CC as a secondary diagnosis (FY2027). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder-derived relationships — computed from published CMS and AHRQ datasets

Other codes that name E89.1 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 1 Excludes1 note: R73 — Elevated blood glucose level.

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 12 Excludes2 notes across 3 chapters: E36 — Intraoperative complications of endocrine system (via E89.-), T80 — Complications following infusion, transfusion and therapeutic injection (via E89.-), T80-T88 — Complications of surgical and medical care, not elsewhere classified (T80-T88) (via E89.-), T81 — Complications of procedures, not elsewhere classified (via E89.-), T82 — Complications of cardiac and vascular prosthetic devices, implants and grafts (via E89.-), T83 — Complications of genitourinary prosthetic devices, implants and grafts (via E89.-), T84 — Complications of internal orthopedic prosthetic devices, implants and grafts (via E89.-), T85 — Complications of other internal prosthetic devices, implants and grafts (via E89.-), T86 — Complications of transplanted organs and tissue (via E89.-), T87 — Complications peculiar to reattachment and amputation (via E89.-), T88 — Other complications of surgical and medical care, not elsewhere classified (via E89.-), Z90 — Acquired absence of organs, not elsewhere classified (via E89.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

MS-DRG Grouper Relationships (FY2027)

Potential MS-DRG participation — not a DRG assignment.

FY2027 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 355 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 5 MS-DRGs: DRG 008 (MDC PRE), DRG 010 (MDC PRE), DRG 019 (MDC PRE), DRG 640 (MDC 10), DRG 641 (MDC 10).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):END014 — Postprocedural or postoperative endocrine or metabolic complication (default); END002 — Diabetes mellitus without complication.

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical categories (Postprocedural or postoperative endocrine or metabolic complication, Diabetes mellitus without complication).

E10.A2 — Type 1 diabetes mellitus, presymptomatic, Stage 2, E11.9 — Type 2 diabetes mellitus without complications, E11.A — Type 2 diabetes mellitus without complications in remission, E13.9 — Other specified diabetes mellitus without complications, E36.01 — Intraoperative hemorrhage and hematoma of an endocrine system organ or structure complicating an endocrine system procedure, E36.02 — Intraoperative hemorrhage and hematoma of an endocrine system organ or structure complicating other procedure, E36.11 — Accidental puncture and laceration of an endocrine system organ or structure during an endocrine system procedure, E36.12 — Accidental puncture and laceration of an endocrine system organ or structure during other procedure, E36.8 — Other intraoperative complications of endocrine system, E89.0 — Postprocedural hypothyroidism, E89.2 — Postprocedural hypoparathyroidism, E89.3 — Postprocedural hypopituitarism, E89.40 — Asymptomatic postprocedural ovarian failure, E89.41 — Symptomatic postprocedural ovarian failure, E89.5 — Postprocedural testicular hypofunction, E89.6 — Postprocedural adrenocortical (-medullary) hypofunction, E89.810 — Postprocedural hemorrhage of an endocrine system organ or structure following an endocrine system procedure, E89.811 — Postprocedural hemorrhage of an endocrine system organ or structure following other procedure, E89.820 — Postprocedural hematoma of an endocrine system organ or structure following an endocrine system procedure, E89.821 — Postprocedural hematoma of an endocrine system organ or structure following other procedure, +53 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Hyperglycemia, hyperglycemic”; these codes share that main term but sit in a different category of the Tabular List.

R73.9 — Hyperglycemia, unspecified

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

HbA1c Test (Glycated Hemoglobin), Blood Glucose Test

Contextual Map

Every relationship of E89.1 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run E89.1 with these 14 related codes in Claim Check

Hierarchy

Excludes1

Code First

Use Additional Code

Referenced by Excludes1 notes

Referenced by Excludes2 notes (12)

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • Pre-MDC[MDC crossing]: “Pre-MDC — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 175 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027
  • MDC 10 — Endocrine, Nutritional and Metabolic Diseases and Disorders[MDC crossing]: “Endocrine, Nutritional and Metabolic Diseases and Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 5,013 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027

Index entries

  • Complication (s) (from) (of), endocrine, postprocedural, hypoinsulinemia[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Complication (s) (from) (of), surgical procedure (on), hyperglycemia (postpancreatectomy)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Complication (s) (from) (of), surgical procedure (on), hypoinsulinemia (postpancreatectomy)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Hyperglycemia, hyperglycemic (transient), postpancreatectomy[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Hypoinsulinemia, postprocedural[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Postpancreatectomy hyperglycemia[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Postprocedural, hypoinsulinemia[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027

Nearest codes (22)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Relevant guides

Reference

Index terms and tables, published questions and FAQ, every source behind this page with its release and checksum, the date-of-service check and the complete change history.

Indexed Clinical Terms (7)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
Coding guidelines Official source data
ICD-10-CM Official Guidelines for Coding and Reporting (FY2027), quoted by section Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder-derived relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder editorial explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources

Labels on this page: Official source data · MedCoder-derived relationship · MedCoder editorial explanation. How to read the labels · All data sources and release dates · CMS coding rules

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "E89.1 — Postprocedural hypoinsulinemia." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/e89.1-postprocedural-hypoinsulinemia

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Postprocedural hypoinsulinemia

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027, and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to E89.1 in its code family, with their registry titles.

View all codes in the E89 family