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I25.700 ICD-10-CM Code: Atherosclerosis of coronary artery bypass graft(s), unspecified, with unstable angina pectoris

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Risk Adjustment (CMS-HCC)

Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.

  • HCC 229 — Unstable Angina and Other Acute Ischemic Heart Disease

Other models: CMS-HCC V22 HCC 87 · RxHCC V08 HCC 188

Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for I25.700 in the official ICD-10-CM tabular list, quoted as published.

Notes without a marker are published on I25.700 itself; “inherited from” names the category or block whose note applies here.

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Source: inherited from I25

Code Also

Additional codes that may be required to fully describe the encounter.

  • the presence of hypertension (I10-I1A)

Source: inherited from I20-I25

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code, if applicable, to identify:
  • coronary atherosclerosis due to calcified coronary lesion (I25.84) inherited from I25.7
  • coronary atherosclerosis due to lipid rich plaque (I25.83) inherited from I25.7
  • Use additional code to identify:
  • chronic total occlusion of coronary artery (I25.82) inherited from I25
  • exposure to environmental tobacco smoke (Z77.22) inherited from I25
  • history of tobacco dependence (Z87.891) inherited from I25
  • occupational exposure to environmental tobacco smoke (Z57.31) inherited from I25
  • tobacco dependence (F17.-) inherited from I25
  • tobacco use (Z72.0) inherited from I25

Code Overview

Atherosclerosis of coronary artery bypass graft(s), unspecified, with unstable angina pectoris is a billable ICD-10-CM diagnosis code (I25.700).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (1)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Official Coding Guidelines

Verbatim excerpts from the ICD-10-CM Official Guidelines for Coding and Reporting (CMS/NCHS) that govern this code.

Chapter 9: Diseases of the Circulatory System (I00 -I99)

b. Atherosclerotic Coronary Artery Disease and Angina ICD-10-CM has combination codes for atherosclerotic heart disease with angina pectoris. The subcategories for these codes are I25.11, Atherosclerotic heart disease of native coronary artery with angina pectoris and I25.7, Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris.

Decision Points

The directives on this code's own record, as a pre-claim checklist.

  1. 10 Use Additional Code instructions — report the named additional code(s) when the documentation supports them. See the Use Additional Code notes
  2. 1 Code Also note — a second code may apply; the guidelines leave its sequencing to the circumstances of the encounter. See the Code Also notes
  3. 4 Excludes1 entries — codes named there are generally not reported together with this code (Guidelines I.A.12.a). See the Excludes1 notes
  4. 1 Excludes2 entry — those conditions are not part of this code and may be reported additionally when documented. See the Excludes2 notes

Checklist rows are derived from this code's own official directives; the wording of each check is MedCoder editorial. The official notes themselves are in the sections each row links to.

Verify Before Coding

  • Age-restricted: the Medicare Code Editor lists this as an adult (age 15-124) diagnosis; other ages are presumed incorrect.
  • CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

Other codes that name I25.700 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 1 Excludes1 note: I20 — Angina pectoris (via I25.7.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 4 Excludes2 notes: I25.1 — Atherosclerotic heart disease of native coronary artery (via I25.7.-), I25.5 — Ischemic cardiomyopathy (via I25.7.-), I74 — Arterial embolism and thrombosis (via I25.-), I82 — Other venous embolism and thrombosis (via I25.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

Referenced by 3 Code First instructions: I25.82 — Chronic total occlusion of coronary artery (via I25.7.-), I25.83 — Coronary atherosclerosis due to lipid rich plaque (via I25.7.-), I25.84 — Coronary atherosclerosis due to calcified coronary lesion (via I25.7.-).

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

MS-DRG Grouper Relationships (FY2026)

CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 65 clinically related codes on its CMS exclusion list.

Potential MS-DRG participation — not a DRG assignment.

Named in the grouper logic of 2 MS-DRGs: DRG 302 (MDC 05), DRG 303 (MDC 05).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):CIR011 — Coronary atherosclerosis and other heart disease (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as CC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

I22.1 — Subsequent ST elevation (STEMI) myocardial infarction of inferior wall, I22.2 — Subsequent non-ST elevation (NSTEMI) myocardial infarction, I22.8 — Subsequent ST elevation (STEMI) myocardial infarction of other sites, I22.9 — Subsequent ST elevation (STEMI) myocardial infarction of unspecified site, I24.0 — Acute coronary thrombosis not resulting in myocardial infarction, I24.81 — Acute coronary microvascular dysfunction, I24.89 — Other forms of acute ischemic heart disease, I24.9 — Acute ischemic heart disease, unspecified, I25.5 — Ischemic cardiomyopathy, I25.6 — Silent myocardial ischemia, I25.702 — Atherosclerosis of coronary artery bypass graft(s), unspecified, with refractory angina pectoris, I25.712 — Atherosclerosis of autologous vein coronary artery bypass graft(s) with refractory angina pectoris, I25.722 — Atherosclerosis of autologous artery coronary artery bypass graft(s) with refractory angina pectoris, I25.732 — Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with refractory angina pectoris, I25.752 — Atherosclerosis of native coronary artery of transplanted heart with refractory angina pectoris, I25.762 — Atherosclerosis of bypass graft of coronary artery of transplanted heart with refractory angina pectoris, I25.792 — Atherosclerosis of other coronary artery bypass graft(s) with refractory angina pectoris, I25.85 — Chronic coronary microvascular dysfunction, I25.89 — Other forms of chronic ischemic heart disease, I25.9 — Chronic ischemic heart disease, unspecified, +44 more

Same CMS-HCC risk category (V28)

CMS maps these diagnoses to the same Hierarchical Condition Category (Unstable Angina and Other Acute Ischemic Heart Disease) for risk-adjusted payment.

I23.3 — Rupture of cardiac wall without hemopericardium as current complication following acute myocardial infarction, I23.4 — Rupture of chordae tendineae as current complication following acute myocardial infarction, I23.5 — Rupture of papillary muscle as current complication following acute myocardial infarction, I23.6 — Thrombosis of atrium, auricular appendage, and ventricle as current complications following acute myocardial infarction, I23.7 — Postinfarction angina, I23.8 — Other current complications following acute myocardial infarction, I24.0 — Acute coronary thrombosis not resulting in myocardial infarction, I24.1 — Dressler's syndrome, I24.81 — Acute coronary microvascular dysfunction, I24.89 — Other forms of acute ischemic heart disease, I24.9 — Acute ischemic heart disease, unspecified, I25.110 — Atherosclerotic heart disease of native coronary artery with unstable angina pectoris, I25.710 — Atherosclerosis of autologous vein coronary artery bypass graft(s) with unstable angina pectoris, I25.720 — Atherosclerosis of autologous artery coronary artery bypass graft(s) with unstable angina pectoris, I25.730 — Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with unstable angina pectoris, I25.750 — Atherosclerosis of native coronary artery of transplanted heart with unstable angina, I25.760 — Atherosclerosis of bypass graft of coronary artery of transplanted heart with unstable angina, I25.790 — Atherosclerosis of other coronary artery bypass graft(s) with unstable angina pectoris, I51.1 — Rupture of chordae tendineae, not elsewhere classified, I51.2 — Rupture of papillary muscle, not elsewhere classified, +4 more

Related risk categories

These categories interact through CMS's HCC hierarchy — one can suppress the other's risk-adjustment weight when both are present on a claim.

Acute Myocardial Infarction

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Coronary atherosclerosis and other heart disease).

I24.9 — Acute ischemic heart disease, unspecified, I25.10 — Atherosclerotic heart disease of native coronary artery without angina pectoris, I25.110 — Atherosclerotic heart disease of native coronary artery with unstable angina pectoris, I25.111 — Atherosclerotic heart disease of native coronary artery with angina pectoris with documented spasm, I25.112 — Atherosclerotic heart disease of native coronary artery with refractory angina pectoris, I25.118 — Atherosclerotic heart disease of native coronary artery with other forms of angina pectoris, I25.119 — Atherosclerotic heart disease of native coronary artery with unspecified angina pectoris, I25.2 — Old myocardial infarction, I25.5 — Ischemic cardiomyopathy, I25.6 — Silent myocardial ischemia, I25.701 — Atherosclerosis of coronary artery bypass graft(s), unspecified, with angina pectoris with documented spasm, I25.702 — Atherosclerosis of coronary artery bypass graft(s), unspecified, with refractory angina pectoris, I25.708 — Atherosclerosis of coronary artery bypass graft(s), unspecified, with other forms of angina pectoris, I25.709 — Atherosclerosis of coronary artery bypass graft(s), unspecified, with unspecified angina pectoris, I25.710 — Atherosclerosis of autologous vein coronary artery bypass graft(s) with unstable angina pectoris, I25.711 — Atherosclerosis of autologous vein coronary artery bypass graft(s) with angina pectoris with documented spasm, I25.712 — Atherosclerosis of autologous vein coronary artery bypass graft(s) with refractory angina pectoris, I25.718 — Atherosclerosis of autologous vein coronary artery bypass graft(s) with other forms of angina pectoris, I25.719 — Atherosclerosis of autologous vein coronary artery bypass graft(s) with unspecified angina pectoris, I25.720 — Atherosclerosis of autologous artery coronary artery bypass graft(s) with unstable angina pectoris, +47 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Arteriosclerosis, arteriosclerotic”; these codes share that main term but sit in a different category of the Tabular List.

G95.19 — Other vascular myelopathies (spinal), I27.0 — Primary pulmonary hypertension (pulmonary), I51.4 — Myocarditis, unspecified (myocarditis), I65.2 — Occlusion and stenosis of carotid artery (carotid), I67.2 — Cerebral atherosclerosis (brain), I70.0 — Atherosclerosis of aorta (aorta), I70.1 — Atherosclerosis of renal artery (renal, artery), I70.201 — Unspecified atherosclerosis of native arteries of extremities, right leg (extremities, leg, right), I70.202 — Unspecified atherosclerosis of native arteries of extremities, left leg (extremities, leg, left), I70.203 — Unspecified atherosclerosis of native arteries of extremities, bilateral legs (extremities, leg, bilateral), I70.208 — Unspecified atherosclerosis of native arteries of extremities, other extremity (extremities, specified site NEC), I70.209 — Unspecified atherosclerosis of native arteries of extremities, unspecified extremity (extremities), I70.211 — Atherosclerosis of native arteries of extremities with intermittent claudication, right leg (extremities, leg, right, with, intermittent claudication), I70.212 — Atherosclerosis of native arteries of extremities with intermittent claudication, left leg (extremities, leg, left, with, intermittent claudication), I70.213 — Atherosclerosis of native arteries of extremities with intermittent claudication, bilateral legs (extremities, leg, bilateral, with, intermittent claudication), I70.218 — Atherosclerosis of native arteries of extremities with intermittent claudication, other extremity (extremities, specified site NEC, with, intermittent claudication), I70.219 — Atherosclerosis of native arteries of extremities with intermittent claudication, unspecified extremity (extremities, leg, with, intermittent claudication), I70.221 — Atherosclerosis of native arteries of extremities with rest pain, right leg (with, critical limb ischemia, leg, right), I70.222 — Atherosclerosis of native arteries of extremities with rest pain, left leg (with, critical limb ischemia, leg, left), I70.223 — Atherosclerosis of native arteries of extremities with rest pain, bilateral legs (extremities, leg, bilateral, with, rest pain), +231 more

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

Blood Glucose Test, Lipid Panel, Prothrombin Time Test and INR (PT/INR)

Contextual Map

Every relationship of I25.700 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run I25.700 with these 9 related codes in Claim Check

Hierarchy

Excludes1

  • I20.0 — Unstable angina[Excludes1]: “unstable angina pectoris without atherosclerosis of coronary artery bypass graft (I20.0)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Referenced by Excludes1 notes

  • I20 — Angina pectoris[Excludes1](via I25.7.-): “atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris (I25.7-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Referenced by Excludes2 notes

Referenced by Code First instructions

Clinical classification (CCSR)

Risk adjustment (CMS-HCC)

  • HCC 229 — Unstable Angina and Other Acute Ischemic Heart Disease [CMS-HCC]— CMS-HCC V28 · 2026

MS-DRG Grouper

  • CC — Complication or Comorbidity [MS-DRG severity]: “As a secondary diagnosis this code can raise the stay's MS-DRG severity tier (CC).”— CMS MS-DRG Definitions Manual (Appendix C) · FY2026
  • DRG 302 — ATHEROSCLEROSIS WITH MCC[MS-DRG]: “ATHEROSCLEROSIS WITH MCC (MDC 05)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • DRG 303 — ATHEROSCLEROSIS WITHOUT MCC[MS-DRG]: “ATHEROSCLEROSIS WITHOUT MCC (MDC 05)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026

MDC crossing

  • MDC 05 — Diseases and Disorders of the Circulatory System[MDC crossing]: “Diseases and Disorders of the Circulatory System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 17,209 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

  • Arteriosclerosis, arteriosclerotic (diffuse) (obliterans) (of) (senile) (with calcification), coronary (artery), bypass graft, with, angina pectoris, unstable[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes (40)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Coding guidelines Official source data
ICD-10-CM Official Guidelines for Coding and Reporting (FY2026), quoted by section Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
Risk adjustment Official source data
2026 Mid-Year Final ICD-10 Mappings + Model Software (cms.gov/files/zip/2026-midyear-final-icd-10-mappings.zip, 2026-midyear-final-model-software.zip) — CMS-HCC V28, PY2026 mid-year final release Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Atherosclerosis of coronary artery bypass graft(s), unspecified, with unstable angina pectoris

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to I25.700 in its code family, with their registry titles.

View all codes in the I25 family