O60.22X0 ICD-10-CM Code: Term delivery with preterm labor, second trimester, not applicable or unspecified
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Inpatient Payment Groups (MS-DRG)
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.
- MS-DRG 998 — PRINCIPAL DIAGNOSIS INVALID AS DISCHARGE DIAGNOSIS (MDC 14)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Official Registry Overview & Definition
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for O60.22X0 in the official ICD-10-CM tabular list.
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- onset (spontaneous) of labor before 37 completed weeks of gestation
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- false labor (O47.0-) Compare O60.22X0 vs O47.0 →
- threatened labor NOS (O47.0-) Compare O60.22X0 vs O47.0 →
Frequently Compared Codes
The official Excludes notes on O60.22X0 name these codes. Each comparison page covers when the two can — or must not — be reported together.
Change history
No changes recorded for this code — unchanged since the FY2016 baseline of the change ledger.
Verify Before Coding
- Age-restricted: the Medicare Code Editor lists this as a maternity (age 9-64) diagnosis; other ages are presumed incorrect.
- MCC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.
Relationships & Classification
Official ICD-10-CM tabular notes on other codes that name O60.22X0 or its code family.
1 Excludes1 notes: O47 (via O60.-).
Potential MS-DRG Relationships (FY2026)
MCC — Major Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 277 clinically related codes on its CMS exclusion list.
Named in the grouper logic of 1 MS-DRG: DRG 998 (MDC 14).
From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.
Clinical classification (AHRQ CCSR):PRG011 — Early or threatened labor (default); PRG029 — Uncomplicated pregnancy, delivery or puerperium.
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Contextual Map
Every relationship of O60.22X0 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Hierarchy
- O00-O9A — Chapter 15: Pregnancy, Childbirth and the Puerperium (O00-O9A) (O00-O9A) [Hierarchy]
- O60-O77 — Complications of labor and delivery [Hierarchy]
- O60 — Clinical Diagnosis [Hierarchy]
- O60.2 — Clinical Diagnosis [Hierarchy]
- O60.22 — Clinical Diagnosis [Hierarchy]
- O60.22X — Clinical Diagnosis [Hierarchy]
Referenced by Excludes1 notes
- O47 — False labor [Excludes1](via O60.-): “preterm labor (O60.-)” · check together
Clinical classification (CCSR)
- PRG011 — Early or threatened labor [CCSR]
- PRG029 — Uncomplicated pregnancy, delivery or puerperium [CCSR]
Potential MS-DRG
- MCC — Major Complication or Comorbidity [MS-DRG severity]: “As a secondary diagnosis this code can raise the stay's MS-DRG severity tier (MCC).”
- DRG 998 — PRINCIPAL DIAGNOSIS INVALID AS DISCHARGE DIAGNOSIS [MS-DRG]: “PRINCIPAL DIAGNOSIS INVALID AS DISCHARGE DIAGNOSIS (MDC 14)”
Nearest codes (40)
- O60 — Preterm labor [Sibling]
- O60.13 — Preterm labor second trimester with preterm delivery third trimester [Sibling]
- O60.13X0 — Preterm labor second trimester with preterm delivery third trimester, not applicable or unspecified [Sibling]
- O60.13X1 — Preterm labor second trimester with preterm delivery third trimester, fetus 1 [Sibling]
- O60.13X2 — Preterm labor second trimester with preterm delivery third trimester, fetus 2 [Sibling]
- O60.13X3 — Preterm labor second trimester with preterm delivery third trimester, fetus 3 [Sibling]
- O60.13X4 — Preterm labor second trimester with preterm delivery third trimester, fetus 4 [Sibling]
- O60.13X5 — Preterm labor second trimester with preterm delivery third trimester, fetus 5 [Sibling]
- and 32 more
Frequently Asked Questions (FAQ) & Clinical Guidance
Does O60.22X0 require a 7th character?
Yes. One of the following 7th characters is to be assigned to each code under subcategory O60.2. 7th character 0 is for single gestations and multiple gestations where the fetus is unspecified. 7th characters 1 through 9 are for cases of multiple gestations to identify the fetus for which the code applies. The appropriate code from category O30, Multiple gestation, must also be assigned when assigning a code from subcategory O60.2 that has a 7th character of 1 through 9..
Nearest Codes in This Family
Official ICD-10-CM classifications closest to O60.22X0 in its code family, with their registry titles.
- O60.20X3 — Term delivery with preterm labor, unspecified trimester, fetus 3
- O60.20X4 — Term delivery with preterm labor, unspecified trimester, fetus 4
- O60.20X5 — Term delivery with preterm labor, unspecified trimester, fetus 5
- O60.20X9 — Term delivery with preterm labor, unspecified trimester, other fetus
- O60.22 — Term delivery with preterm labor, second trimester
- O60.22X1 — Term delivery with preterm labor, second trimester, fetus 1
- O60.22X2 — Term delivery with preterm labor, second trimester, fetus 2
- O60.22X3 — Term delivery with preterm labor, second trimester, fetus 3
- O60.22X4 — Term delivery with preterm labor, second trimester, fetus 4
- O60.22X5 — Term delivery with preterm labor, second trimester, fetus 5