T36.0X5A ICD-10-CM Code: Adverse effect of penicillins, initial encounter
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Inpatient Payment Groups (MS-DRG)
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.
- MS-DRG 791 — PREMATURITY WITH MAJOR PROBLEMS (MDC 15)
- MS-DRG 793 — FULL TERM NEONATE WITH MAJOR PROBLEMS (MDC 15)
- MS-DRG 917 — POISONING AND TOXIC EFFECTS OF DRUGS WITH MCC (MDC 21)
- MS-DRG 918 — POISONING AND TOXIC EFFECTS OF DRUGS WITHOUT MCC (MDC 21)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.
Official Registry Overview & Definition
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for T36.0X5A in the official ICD-10-CM tabular list.
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- adverse effect of correct substance properly administered
- poisoning by overdose of substance
- poisoning by wrong substance given or taken in error
- underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- antineoplastic antibiotics (T45.1-)
- locally applied antibiotic NEC (T49.0)
- topically used antibiotic for ear, nose and throat (T49.6)
- topically used antibiotic for eye (T49.5)
- toxic reaction to local anesthesia in pregnancy (O29.3-)
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- abuse and dependence of psychoactive substances (F10-F19)
- abuse of non-dependence-producing substances (F55.-)
- immunodeficiency due to drugs (D84.821)
- drug reaction and poisoning affecting newborn (P00-P96)
- pathological drug intoxication (inebriation) (F10-F19)
Code First
Underlying conditions that must be sequenced before this code.
- Code first, for adverse effects, the nature of the adverse effect, such as:
- adverse effect NOS (T88.7)
- aspirin gastritis (K29.-)
- blood disorders (D56-D76)
- contact dermatitis (L23-L25)
- dermatitis due to substances taken internally (L27.-)
- nephropathy (N14.0-N14.2)
Use Additional Code
Supplementary codes the tabular list directs you to add.
- Use additional code(s) to specify:
- manifestations of poisoning
- underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
- underdosing of medication regimen (Z91.12-, Z91.13-)
Frequently Asked Questions (FAQ) & Clinical Guidance
Does T36.0X5A require a 7th character?
Yes. The appropriate 7th character is to be added to each code from category T36.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to T36.0X5A in its code family, with their registry titles.
- T36.0X4 — Poisoning by penicillins, undetermined
- T36.0X4A — Poisoning by penicillins, undetermined, initial encounter
- T36.0X4D — Poisoning by penicillins, undetermined, subsequent encounter
- T36.0X4S — Poisoning by penicillins, undetermined, sequela
- T36.0X5 — Adverse effect of penicillins
- T36.0X5D — Adverse effect of penicillins, subsequent encounter
- T36.0X5S — Adverse effect of penicillins, sequela
- T36.0X6 — Underdosing of penicillins
- T36.0X6A — Underdosing of penicillins, initial encounter
- T36.0X6D — Underdosing of penicillins, subsequent encounter
Associated Substances (54)
Substances from the official ICD-10-CM Table of Drugs and Chemicals that map to this code.
- Adicillin
- Amdinocilline
- Amoxicillin
- Ampicillin
- Ancillin
- Apalcillin
- Aspoxicillin
- Azidocillin
- Azlocillin
- Bacampicillin
- Benethamine penicillin
- Benzathine benzylpenicillin
- Benzathine penicillin
- Benzylpenicillin
- Carbenicillin
- Carfecillin
- Carindacillin
- Ciclacillin
- Clometocillin
- Cloxacillin
- Cyclacillin
- Dicloxacillin
- Epicillin
- Flucloxacillin
- Hetacillin
- Hydrabamine penicillin
- Imipenem
- Isoxazolyl penicillin
- Mecillinam
- Metampicillin
- Methicillin
- Methoxybenzyl penicillin
- Meticillin
- Mezlocillin
- Nafcillin
- Oxacillin
- Penamecillin
- Penethamate
- Penicillin (any)
- Phenbenicillin
- Pheneticillin
- Phenoxymethyl penicillin
- Phenthicillin
- Piperacillin
- Pivampicillin
- Pivmecillinam
- Propicillin
- Sulbactam
- Sulbenicillin
- Sultamicillin
- Talampicillin
- Temocillin
- Ticarcillin
- Xantocillin