T40.422S ICD-10-CM Code: Poisoning by tramadol, intentional self-harm, sequela
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Inpatient Payment Groups (MS-DRG)
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.
- MS-DRG 922 — OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITH MCC (MDC 21)
- MS-DRG 923 — OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITHOUT MCC (MDC 21)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Official Registry Overview & Definition
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for T40.422S in the official ICD-10-CM tabular list.
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- adverse effect of correct substance properly administered
- poisoning by overdose of substance
- poisoning by wrong substance given or taken in error
- underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- toxic reaction to local anesthesia in pregnancy (O29.3-) Compare T40.422S vs O29.3 →
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- drug dependence and related mental and behavioral disorders due to psychoactive substance use (F10.-F19.-) Compare T40.422S vs F10 →
- abuse and dependence of psychoactive substances (F10-F19) Compare T40.422S vs F10 →
- abuse of non-dependence-producing substances (F55.-) Compare T40.422S vs F55 →
- immunodeficiency due to drugs (D84.821) Compare T40.422S vs D84.821 →
- drug reaction and poisoning affecting newborn (P00-P96) Compare T40.422S vs P00 →
- pathological drug intoxication (inebriation) (F10-F19) Compare T40.422S vs F10 →
Code First
Underlying conditions that must be sequenced before this code.
Associated Substances (1)
Substances from the official ICD-10-CM Table of Drugs and Chemicals that map to this code.
- Tramadol
Frequently Compared Codes
The official Excludes notes on T40.422S name these codes. Each comparison page covers when the two can — or must not — be reported together.
Change history
- FY2021 — 2020-10-01Added to the code setPoisoning by tramadol, intentional self-harm, sequelaFY2021 changes
Verify Before Coding
- No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.
Relationships & Classification
Clinical classification (AHRQ CCSR):MBD034 — Mental and substance use disorders; sequela (default); INJ075 — Poisoning/toxic effect/adverse effects/underdosing, sequela.
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Potential MS-DRG Relationships (FY2026)
Not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity.
Named in the grouper logic of 2 MS-DRGs: DRG 922 (MDC 21), DRG 923 (MDC 21).
From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.
Contextual Map
Every relationship of T40.422S in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Hierarchy
- S00-T88 — Chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) (S00-T88) [Hierarchy]
- T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances [Hierarchy]
- T40-T41 — Analgesics & Antipyretics [Hierarchy]
Clinical classification (CCSR)
- MBD034 — Mental and substance use disorders; sequela [CCSR]
- INJ075 — Poisoning/toxic effect/adverse effects/underdosing, sequela [CCSR]
Potential MS-DRG
- DRG 922 — OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITH MCC [MS-DRG]: “OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITH MCC (MDC 21)”
- DRG 923 — OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITHOUT MCC [MS-DRG]: “OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITHOUT MCC (MDC 21)”
MDC crossing · procedures (32029)
- MDC 21 — Injuries, Poisonings and Toxic Effects of Drugs [MDC crossing]: “Injuries, Poisonings and Toxic Effects of Drugs — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”
- 0016070 — Bypass Cerebral Ventricle to Nasopharynx with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Nasopharynx with Autologous Tissue Substitute, Open Approach — grouped in MDC 21, the procedure side of this code's crossing.” · check together
- 0016071 — Bypass Cerebral Ventricle to Mastoid Sinus with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Mastoid Sinus with Autologous Tissue Substitute, Open Approach — grouped in MDC 21, the procedure side of this code's crossing.” · check together
- 0016072 — Bypass Cerebral Ventricle to Atrium with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Atrium with Autologous Tissue Substitute, Open Approach — grouped in MDC 21, the procedure side of this code's crossing.” · check together
- 0016073 — Bypass Cerebral Ventricle to Blood Vessel with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Blood Vessel with Autologous Tissue Substitute, Open Approach — grouped in MDC 21, the procedure side of this code's crossing.” · check together
- 0016074 — Bypass Cerebral Ventricle to Pleural Cavity with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Pleural Cavity with Autologous Tissue Substitute, Open Approach — grouped in MDC 21, the procedure side of this code's crossing.” · check together
- and 32024 more
Drugs & chemicals
- Tramadol — Tramadol — Poisoning, Intentional self-harm [Drug table]: “Tramadol (Poisoning, Intentional self-harm)”
Nearest codes (40)
- T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens] [Sibling]
- T40.414 — Poisoning by fentanyl or fentanyl analogs, undetermined [Sibling]
- T40.414A — Poisoning by fentanyl or fentanyl analogs, undetermined, initial encounter [Sibling]
- T40.414D — Poisoning by fentanyl or fentanyl analogs, undetermined, subsequent encounter [Sibling]
- T40.414S — Poisoning by fentanyl or fentanyl analogs, undetermined, sequela [Sibling]
- T40.415 — Adverse effect of fentanyl or fentanyl analogs [Sibling]
- T40.415A — Adverse effect of fentanyl or fentanyl analogs, initial encounter [Sibling]
- T40.415D — Adverse effect of fentanyl or fentanyl analogs, subsequent encounter [Sibling]
- and 32 more
Change history
- FY2021 — Added to the code set [Change history]
Frequently Asked Questions (FAQ) & Clinical Guidance
Does T40.422S require a 7th character?
Yes. The appropriate 7th character is to be added to each code from category T40.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to T40.422S in its code family, with their registry titles.
- T40.421D — Poisoning by tramadol, accidental (unintentional), subsequent encounter
- T40.421S — Poisoning by tramadol, accidental (unintentional), sequela
- T40.422 — Poisoning by tramadol, intentional self-harm
- T40.422A — Poisoning by tramadol, intentional self-harm, initial encounter
- T40.422D — Poisoning by tramadol, intentional self-harm, subsequent encounter
- T40.423 — Poisoning by tramadol, assault
- T40.423A — Poisoning by tramadol, assault, initial encounter
- T40.423D — Poisoning by tramadol, assault, subsequent encounter
- T40.423S — Poisoning by tramadol, assault, sequela
- T40.424 — Poisoning by tramadol, undetermined