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D56 ICD-10-CM Code: Thalassemia

Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.

Coding at a Glance

Tabular directives
1 Excludes1

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for D56 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Coder workflow for D56

MedCoder structured workflow — derived from this code’s own official record

Before you code D56

  1. D56 is not reportable as written. Select the more specific code beneath it that the documentation supports. Codes are reported to the highest level of specificity the classification provides (Guidelines I.B.2).

    ReviewD56.0, D56.1, D56.2, D56.3, D56.4, D56.5, D56.8, D56.9

    See the relationships section · Guide: How to choose an ICD-10-CM code →

  2. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with D56. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

    See the official tabular notes

Choose the right path

  1. Does the documentation support one of the more specific codes beneath D56?
    Yes → Select that code and continue the checks below on its own page.
    No → D56 cannot be reported as written; query for the specificity its subcategory needs.

    ReviewD56.0, D56.1, D56.2, D56.3, D56.4, D56.5, D56.8, D56.9

  2. Does the documentation support a condition named in D56’s Excludes1 note?
    Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
    No → Continue.

    ReviewD57.4

Consider D56. Then confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

Official instructions as workflow

  • Excludes1 — check before selecting D56(1 note)

    Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with D56: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

    CompareD57.4

    See the official tabular notes · Guidelines I.A.12.a

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: Both the condition D56 describes and a condition named in its Excludes1 note are documented for the same encounter.

Coding question: Can both codes be reported?

Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.

Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).

ReviewD57.4

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Code Overview

Thalassemia is a non-billable ICD-10-CM category code (D56). A more specific billable subcode must be selected for claims submission.

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Verify Before Coding

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name D56 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 14 Excludes1 notes across 2 chapters: P50 — Newborn affected by intrauterine (fetal) blood loss, P50-P61 — Hemorrhagic and hematological disorders of newborn (P50-P61), P51 — Umbilical hemorrhage of newborn, P52 — Intracranial nontraumatic hemorrhage of newborn, P53 — Hemorrhagic disease of newborn, P54 — Other neonatal hemorrhages, P55 — Hemolytic disease of newborn, P56 — Hydrops fetalis due to hemolytic disease, P57 — Kernicterus, P58 — Neonatal jaundice due to other excessive hemolysis, P59 — Neonatal jaundice from other and unspecified causes, P60 — Disseminated intravascular coagulation of newborn, P61 — Other perinatal hematological disorders, R71 — Abnormality of red blood cells.

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 24 Code First instructions across 3 chapters: I21.A1 — Myocardial infarction type 2, M36.3 — Arthropathy in other blood disorders, M90.5 — Osteonecrosis in diseases classified elsewhere, T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics, T36-T39 — Antibiotics & Anti-infectives (T36-T39), T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50), T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics, T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified, T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics, T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens], T40-T41 — Analgesics & Antipyretics (T40-T41), T41 — Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases, T42 — Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs, T42-T43 — Anticonvulsants & Psychotropics (T42-T43), T43 — Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified, T44 — Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system, T44-T46 — Cardiovascular & Gastrointestinal (T44-T46), T45 — Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified, T46 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system, T47 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system, +4 more.

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

Contextual Map

Every relationship of D56 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run D56 with these 17 related codes in Claim Check

Hierarchy

Excludes1

Referenced by Excludes1 notes (14)

Referenced by Code First instructions (24)

Nearest codes

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Common coding questions

Can D56 be billed directly?

No. D56 (Thalassemia) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "D56 — Thalassemia." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/d56-thalassemia

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Thalassemia

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to D56 in its code family, with their registry titles.