T80.82XD ICD-10-CM Code: Complication of immune effector cellular therapy, subsequent encounter
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Inpatient Payment Groups (MS-DRG)
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.
- MS-DRG 949 — AFTERCARE WITH CC/MCC (MDC 23)
- MS-DRG 950 — AFTERCARE WITHOUT CC/MCC (MDC 23)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Official Registry Overview & Definition
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for T80.82XD in the official ICD-10-CM tabular list.
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- complications following perfusion
Inclusion Terms
Alternative terms the tabular list files under this code.
- Complication of chimeric antigen receptor (CAR-T) cell therapy
- Complication of IEC therapy
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- adverse effect of immune checkpoint inhibitors and immunostimulant drugs (T45.AX5) Compare T80.82XD vs T45.AX5 →
- complication of bone marrow transplant (T86.0) Compare T80.82XD vs T86.0 →
- complication of stem cell transplant (T86.5) Compare T80.82XD vs T86.5 →
- bone marrow transplant rejection (T86.01) Compare T80.82XD vs T86.01 →
- febrile nonhemolytic transfusion reaction (R50.84) Compare T80.82XD vs R50.84 →
- fluid overload due to transfusion (E87.71) Compare T80.82XD vs E87.71 →
- posttransfusion purpura (D69.51) Compare T80.82XD vs D69.51 →
- transfusion associated circulatory overload (TACO) (E87.71) Compare T80.82XD vs E87.71 →
- transfusion (red blood cell) associated hemochromatosis (E83.111) Compare T80.82XD vs E83.111 →
- transfusion related acute lung injury (TRALI) (J95.84) Compare T80.82XD vs J95.84 →
- any encounters with medical care for postprocedural conditions in which no complications are present, such as:
- artificial opening status (Z93.-) Compare T80.82XD vs Z93 →
- closure of external stoma (Z43.-) Compare T80.82XD vs Z43 →
- fitting and adjustment of external prosthetic device (Z44.-) Compare T80.82XD vs Z44 →
- burns and corrosions from local applications and irradiation (T20-T32) Compare T80.82XD vs T20 →
- complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A) Compare T80.82XD vs O00 →
- mechanical complication of respirator ventilator
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6) Compare T80.82XD vs T36 →
- postprocedural fever (R50.82) Compare T80.82XD vs R50.82 →
- specified complications classified elsewhere, such as:
- cerebrospinal fluid leak from spinal puncture (G97.0) Compare T80.82XD vs G97.0 →
- colostomy malfunction (K94.0-) Compare T80.82XD vs K94.0 →
- disorders of fluid and electrolyte imbalance (E86-E87) Compare T80.82XD vs E86 →
- functional disturbances following cardiac surgery (I97.0-I97.1) Compare T80.82XD vs I97.0 →
- intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-) Compare T80.82XD vs D78 →
- ostomy complications (J95.0-, K94.-, N99.5-) Compare T80.82XD vs J95.0 →
- postgastric surgery syndromes (K91.1) Compare T80.82XD vs K91.1 →
- postlaminectomy syndrome NEC (M96.1) Compare T80.82XD vs M96.1 →
- postmastectomy lymphedema syndrome (I97.2) Compare T80.82XD vs I97.2 →
- postsurgical blind-loop syndrome (K91.2) Compare T80.82XD vs K91.2 →
- ventilator associated pneumonia (J95.851) Compare T80.82XD vs J95.851 →
Use Additional Code
Supplementary codes the tabular list directs you to add.
- Use additional code to identify the specific complication, such as:
- cytokine release syndrome (D89.83-)
- immune effector cell-associated neurotoxicity syndrome (G92.0-)
- Use additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- Use additional code(s) to identify the specified condition resulting from the complication
- Use additional code to identify devices involved and details of circumstances (Y62-Y82)
Change history
- FY2022 — 2021-10-01Added to the code setComplication of immune effector cellular therapy, subsequent encounterFY2022 changes
Verify Before Coding
- Billable — reportable as written.
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.
Referenced by Other Codes
Clinical classification (AHRQ CCSR):INJ072 — Complication of other surgical or medical care, injury, subsequent encounter (default).
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Potential MS-DRG Relationships (FY2026)
Not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity.
Named in the grouper logic of 2 MS-DRGs: DRG 949 (MDC 23), DRG 950 (MDC 23).
From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.
Official ICD-10-CM tabular notes on other codes that name T80.82XD or its code family.
1 Excludes1 notes: T88.7 (via T80.-).
5 Excludes2 notes: T45.8 (via T80.-), T78 (via T80.-), T79 (via T80.-), T81 (via T80.-), T88 (via T80.-).
Frequently Asked Questions (FAQ) & Clinical Guidance
Does T80.82XD require a 7th character?
Yes. The appropriate 7th character is to be added to each code from category T80.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to T80.82XD in its code family, with their registry titles.
- T80.818A — Extravasation of other vesicant agent, initial encounter
- T80.818D — Extravasation of other vesicant agent, subsequent encounter
- T80.818S — Extravasation of other vesicant agent, sequela
- T80.82 — Complication of immune effector cellular therapy
- T80.82XA — Complication of immune effector cellular therapy, initial encounter
- T80.82XS — Complication of immune effector cellular therapy, sequela
- T80.89 — Other complications following infusion, transfusion and therapeutic injection
- T80.89XA — Other complications following infusion, transfusion and therapeutic injection, initial encounter
- T80.89XD — Other complications following infusion, transfusion and therapeutic injection, subsequent encounter
- T80.89XS — Other complications following infusion, transfusion and therapeutic injection, sequela