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ICD-10/T80.82XA

T80.82XA ICD-10-CM Code: Complication of immune effector cellular therapy, initial encounter

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.

  • MS-DRG 791 — PREMATURITY WITH MAJOR PROBLEMS (MDC 15)
  • MS-DRG 793 — FULL TERM NEONATE WITH MAJOR PROBLEMS (MDC 15)
  • MS-DRG 814 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH MCC (MDC 16)
  • MS-DRG 815 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH CC (MDC 16)
  • MS-DRG 816 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITHOUT CC/MCC (MDC 16)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Official Registry Overview & Definition

Complication of immune effector cellular therapy, initial encounter is a billable ICD-10-CM diagnosis code (T80.82A).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for T80.82XA in the official ICD-10-CM tabular list.

Includes

Conditions the official ICD-10-CM tabular list includes under this code.

  • complications following perfusion

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Complication of chimeric antigen receptor (CAR-T) cell therapy
  • Complication of IEC therapy

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code to identify the specific complication, such as:
  • cytokine release syndrome (D89.83-)
  • immune effector cell-associated neurotoxicity syndrome (G92.0-)
  • Use additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • Use additional code(s) to identify the specified condition resulting from the complication
  • Use additional code to identify devices involved and details of circumstances (Y62-Y82)

Change history

  • FY2022 — 2021-10-01
    Added to the code set
    Complication of immune effector cellular therapy, initial encounter
    FY2022 changes

Verify Before Coding

  • Billable — reportable as written.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.

Contextual Map

Every relationship of T80.82XA in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Hierarchy

  • S00-T88 — Chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) (S00-T88) [Hierarchy]
  • T80-T88 — Complications of surgical and medical care, not elsewhere classified [Hierarchy]

Referenced by Excludes1 notes

  • T88.7 — Unspecified adverse effect of drug or medicament [Excludes1](via T80.-): “specified adverse effects of drugs and medicaments (A00-R94 and T80-T88.6, T88.8)”

Referenced by Excludes2 notes

  • T45.8 — Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents [Excludes2](via T80.-): “transfusion reactions (T80.-)”
  • T78 — Adverse effects, not elsewhere classified [Excludes2](via T80.-): “complications of surgical and medical care NEC (T80-T88)”
  • T79 — Certain early complications of trauma, not elsewhere classified [Excludes2](via T80.-): “complications occurring during or following medical procedures (T80-T88)”
  • T81 — Complications of procedures, not elsewhere classified [Excludes2](via T80.-): “complications following infusion, transfusion and therapeutic injection (T80.-)”
  • T88 — Other complications of surgical and medical care, not elsewhere classified [Excludes2](via T80.-): “complication following infusion, transfusion and therapeutic injection (T80.-)”

Clinical classification (CCSR)

  • INJ037 — Complication of other surgical or medical care, injury, initial encounter [CCSR]

Potential MS-DRG

  • DRG 791 — PREMATURITY WITH MAJOR PROBLEMS [MS-DRG]: “PREMATURITY WITH MAJOR PROBLEMS (MDC 15)”
  • DRG 793 — FULL TERM NEONATE WITH MAJOR PROBLEMS [MS-DRG]: “FULL TERM NEONATE WITH MAJOR PROBLEMS (MDC 15)”
  • DRG 814 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH MCC [MS-DRG]: “RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH MCC (MDC 16)”
  • DRG 815 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH CC [MS-DRG]: “RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH CC (MDC 16)”
  • DRG 816 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITHOUT CC/MCC [MS-DRG]: “RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITHOUT CC/MCC (MDC 16)”

Nearest codes (40)

  • T80 — Complications following infusion, transfusion and therapeutic injection [Sibling]
  • T80.61XS — Other serum reaction due to administration of blood and blood products, sequela [Sibling]
  • T80.62 — Other serum reaction due to vaccination [Sibling]
  • T80.62XA — Other serum reaction due to vaccination, initial encounter [Sibling]
  • T80.62XD — Other serum reaction due to vaccination, subsequent encounter [Sibling]
  • T80.62XS — Other serum reaction due to vaccination, sequela [Sibling]
  • T80.69 — Other serum reaction due to other serum [Sibling]
  • T80.69XA — Other serum reaction due to other serum, initial encounter [Sibling]
  • and 32 more

Change history

  • FY2022 — Added to the code set [Change history]

Referenced by Other Codes

Clinical classification (AHRQ CCSR):INJ037 — Complication of other surgical or medical care, injury, initial encounter (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Potential MS-DRG Relationships (FY2026)

Not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity.

Named in the grouper logic of 5 MS-DRGs: DRG 791 (MDC 15), DRG 793 (MDC 15), DRG 814 (MDC 16), DRG 815 (MDC 16), DRG 816 (MDC 16).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Official ICD-10-CM tabular notes on other codes that name T80.82XA or its code family.

1 Excludes1 notes: T88.7 (via T80.-).

5 Excludes2 notes: T45.8 (via T80.-), T78 (via T80.-), T79 (via T80.-), T81 (via T80.-), T88 (via T80.-).

Frequently Asked Questions (FAQ) & Clinical Guidance

Does T80.82XA require a 7th character?

Yes. The appropriate 7th character is to be added to each code from category T80.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to T80.82XA in its code family, with their registry titles.

  • T80.818 — Extravasation of other vesicant agent
  • T80.818A — Extravasation of other vesicant agent, initial encounter
  • T80.818D — Extravasation of other vesicant agent, subsequent encounter
  • T80.818S — Extravasation of other vesicant agent, sequela
  • T80.82 — Complication of immune effector cellular therapy
  • T80.82XD — Complication of immune effector cellular therapy, subsequent encounter
  • T80.82XS — Complication of immune effector cellular therapy, sequela
  • T80.89 — Other complications following infusion, transfusion and therapeutic injection
  • T80.89XA — Other complications following infusion, transfusion and therapeutic injection, initial encounter
  • T80.89XD — Other complications following infusion, transfusion and therapeutic injection, subsequent encounter

View all codes in the T80 family