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T80.90XA ICD-10-CM Code: Unspecified complication following infusion and therapeutic injection, initial encounter

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.

  • MS-DRG 314 — OTHER CIRCULATORY SYSTEM DIAGNOSES WITH MCC (MDC 05)
  • MS-DRG 315 — OTHER CIRCULATORY SYSTEM DIAGNOSES WITH CC (MDC 05)
  • MS-DRG 316 — OTHER CIRCULATORY SYSTEM DIAGNOSES WITHOUT CC/MCC (MDC 05)
  • MS-DRG 791 — PREMATURITY WITH MAJOR PROBLEMS (MDC 15)
  • MS-DRG 793 — FULL TERM NEONATE WITH MAJOR PROBLEMS (MDC 15)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Official Registry Overview & Definition

Unspecified complication following infusion and therapeutic injection, initial encounter is a billable ICD-10-CM diagnosis code (T80.90A).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for T80.90XA in the official ICD-10-CM tabular list.

Includes

Conditions the official ICD-10-CM tabular list includes under this code.

  • complications following perfusion

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • Use additional code(s) to identify the specified condition resulting from the complication
  • Use additional code to identify devices involved and details of circumstances (Y62-Y82)

Frequently Compared Codes

The official Excludes notes on T80.90XA name these codes. Each comparison page covers when the two can — or must not — be reported together.

Change history

No changes recorded for this code — unchanged since the FY2016 baseline of the change ledger.

Verify Before Coding

  • No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.

Contextual Map

Every relationship of T80.90XA in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Hierarchy

  • S00-T88 — Chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) (S00-T88) [Hierarchy]
  • T80-T88 — Complications of surgical and medical care, not elsewhere classified [Hierarchy]

Referenced by Excludes1 notes

  • T88.7 — Unspecified adverse effect of drug or medicament [Excludes1](via T80.-): “specified adverse effects of drugs and medicaments (A00-R94 and T80-T88.6, T88.8)” · check together

Referenced by Excludes2 notes

  • T45.8 — Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents [Excludes2](via T80.-): “transfusion reactions (T80.-)” · check together
  • T78 — Adverse effects, not elsewhere classified [Excludes2](via T80.-): “complications of surgical and medical care NEC (T80-T88)” · check together
  • T79 — Certain early complications of trauma, not elsewhere classified [Excludes2](via T80.-): “complications occurring during or following medical procedures (T80-T88)” · check together
  • T81 — Complications of procedures, not elsewhere classified [Excludes2](via T80.-): “complications following infusion, transfusion and therapeutic injection (T80.-)” · check together
  • T88 — Other complications of surgical and medical care, not elsewhere classified [Excludes2](via T80.-): “complication following infusion, transfusion and therapeutic injection (T80.-)” · check together

Clinical classification (CCSR)

  • INJ037 — Complication of other surgical or medical care, injury, initial encounter [CCSR]

Potential MS-DRG

  • DRG 314 — OTHER CIRCULATORY SYSTEM DIAGNOSES WITH MCC [MS-DRG]: “OTHER CIRCULATORY SYSTEM DIAGNOSES WITH MCC (MDC 05)”
  • DRG 315 — OTHER CIRCULATORY SYSTEM DIAGNOSES WITH CC [MS-DRG]: “OTHER CIRCULATORY SYSTEM DIAGNOSES WITH CC (MDC 05)”
  • DRG 316 — OTHER CIRCULATORY SYSTEM DIAGNOSES WITHOUT CC/MCC [MS-DRG]: “OTHER CIRCULATORY SYSTEM DIAGNOSES WITHOUT CC/MCC (MDC 05)”
  • DRG 791 — PREMATURITY WITH MAJOR PROBLEMS [MS-DRG]: “PREMATURITY WITH MAJOR PROBLEMS (MDC 15)”
  • DRG 793 — FULL TERM NEONATE WITH MAJOR PROBLEMS [MS-DRG]: “FULL TERM NEONATE WITH MAJOR PROBLEMS (MDC 15)”

MDC crossing · procedures (17209)

  • MDC 05 — Diseases and Disorders of the Circulatory System [MDC crossing]: “Diseases and Disorders of the Circulatory System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”
  • MDC 15 — Newborns and Other Neonates with Conditions Originating in Perinatal Period [MDC crossing]: “Newborns and Other Neonates with Conditions Originating in Perinatal Period — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”
  • 00HE0MZ — Insertion of Neurostimulator Lead into Cranial Nerve, Open Approach [Same-MDC procedure]: “Insertion of Neurostimulator Lead into Cranial Nerve, Open Approach — grouped in MDC 05, the procedure side of this code's crossing.” · check together
  • 00HE3MZ — Insertion of Neurostimulator Lead into Cranial Nerve, Percutaneous Approach [Same-MDC procedure]: “Insertion of Neurostimulator Lead into Cranial Nerve, Percutaneous Approach — grouped in MDC 05, the procedure side of this code's crossing.” · check together
  • 00HE4MZ — Insertion of Neurostimulator Lead into Cranial Nerve, Percutaneous Endoscopic Approach [Same-MDC procedure]: “Insertion of Neurostimulator Lead into Cranial Nerve, Percutaneous Endoscopic Approach — grouped in MDC 05, the procedure side of this code's crossing.” · check together
  • 015K0ZZ — Destruction of Head and Neck Sympathetic Nerve, Open Approach [Same-MDC procedure]: “Destruction of Head and Neck Sympathetic Nerve, Open Approach — grouped in MDC 05, the procedure side of this code's crossing.” · check together
  • 015K3ZZ — Destruction of Head and Neck Sympathetic Nerve, Percutaneous Approach [Same-MDC procedure]: “Destruction of Head and Neck Sympathetic Nerve, Percutaneous Approach — grouped in MDC 05, the procedure side of this code's crossing.” · check together
  • and 17204 more

Nearest codes (40)

  • T80 — Complications following infusion, transfusion and therapeutic injection [Sibling]
  • T80.8 — Other complications following infusion, transfusion and therapeutic injection [Sibling]
  • T80.81 — Extravasation of vesicant agent [Sibling]
  • T80.810 — Extravasation of vesicant antineoplastic chemotherapy [Sibling]
  • T80.810A — Extravasation of vesicant antineoplastic chemotherapy, initial encounter [Sibling]
  • T80.810D — Extravasation of vesicant antineoplastic chemotherapy, subsequent encounter [Sibling]
  • T80.810S — Extravasation of vesicant antineoplastic chemotherapy, sequela [Sibling]
  • T80.818 — Extravasation of other vesicant agent [Sibling]
  • and 32 more

Referenced by Other Codes

Clinical classification (AHRQ CCSR):INJ037 — Complication of other surgical or medical care, injury, initial encounter (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Potential MS-DRG Relationships (FY2026)

Not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity.

Named in the grouper logic of 5 MS-DRGs: DRG 314 (MDC 05), DRG 315 (MDC 05), DRG 316 (MDC 05), DRG 791 (MDC 15), DRG 793 (MDC 15).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Official ICD-10-CM tabular notes on other codes that name T80.90XA or its code family.

1 Excludes1 notes: T88.7 (via T80.-).

5 Excludes2 notes: T45.8 (via T80.-), T78 (via T80.-), T79 (via T80.-), T81 (via T80.-), T88 (via T80.-).

Frequently Asked Questions (FAQ) & Clinical Guidance

Does T80.90XA require a 7th character?

Yes. The appropriate 7th character is to be added to each code from category T80.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to T80.90XA in its code family, with their registry titles.

  • T80.89XA — Other complications following infusion, transfusion and therapeutic injection, initial encounter
  • T80.89XD — Other complications following infusion, transfusion and therapeutic injection, subsequent encounter
  • T80.89XS — Other complications following infusion, transfusion and therapeutic injection, sequela
  • T80.9 — Unspecified complication following infusion, transfusion and therapeutic injection
  • T80.90 — Unspecified complication following infusion and therapeutic injection
  • T80.90XD — Unspecified complication following infusion and therapeutic injection, subsequent encounter
  • T80.90XS — Unspecified complication following infusion and therapeutic injection, sequela
  • T80.91 — Hemolytic transfusion reaction, unspecified incompatibility
  • T80.910 — Acute hemolytic transfusion reaction, unspecified incompatibility
  • T80.910A — Acute hemolytic transfusion reaction, unspecified incompatibility, initial encounter

View all codes in the T80 family