E86 vs T80.82XA
E86 (Volume depletion) compared with T80.82XA (Complication of immune effector cellular therapy, initial encounter), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. T80.82XA carries an Excludes2 note covering E86: “disorders of fluid and electrolyte imbalance (E86-E87)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| E86Volume depletion | T80.82XAComplication of immune effector cellular therapy, initial encounter | |
|---|---|---|
| Billing status | Non-billable header | Billable |
| Classification | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) |
| Definition | Volume depletion is a non-billable ICD-10-CM category code (E86). | Complication of immune effector cellular therapy, initial encounter is a billable ICD-10-CM diagnosis code (T80.82A). |
| 7th character | — | The appropriate 7th character is to be added to each code from category T80 |
| Includes | — | complications following perfusion Complication of chimeric antigen receptor (CAR-T) cell therapy Complication of IEC therapy |
| Use additional code | code(s) for any associated disorders of electrolyte and acid-base balance (E87.-) | code to identify the specific complication, such as: cytokine release syndrome (D89.83-) immune effector cell-associated neurotoxicity syndrome (G92.0-) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources