E86.1 ICD-10-CM Code: Hypovolemia
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Coding at a Glance
- Tabular directives
- 1 inclusion term · 8 Excludes1 · 2 Excludes2 · 1 use-additional code
Inpatient Payment Groups (MS-DRG)
Potential MS-DRG participation — not a DRG assignment.
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.
- MS-DRG 640 — MISCELLANEOUS DISORDERS OF NUTRITION, METABOLISM, FLUIDS AND ELECTROLYTES WITH MCC (MDC 10)
- MS-DRG 641 — MISCELLANEOUS DISORDERS OF NUTRITION, METABOLISM, FLUIDS AND ELECTROLYTES WITHOUT MCC (MDC 10)
- MS-DRG 791 — PREMATURITY WITH MAJOR PROBLEMS (MDC 15)
- MS-DRG 793 — FULL TERM NEONATE WITH MAJOR PROBLEMS (MDC 15)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for E86.1 in the official ICD-10-CM tabular list, quoted as published.
Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025
Notes without a marker are published on E86.1 itself; “inherited from” names the category or block whose note applies here.
Inclusion Terms
Alternative terms the tabular list files under this code.
- Depletion of volume of plasma
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- dehydration of newborn (P74.1) inherited from E86Compare E86.1 vs P74.1 →
- postprocedural hypovolemic shock (T81.19) inherited from E86Compare E86.1 vs T81.19 →
- traumatic hypovolemic shock (T79.4) inherited from E86Compare E86.1 vs T79.4 →
- androgen insensitivity syndrome (E34.5-) inherited from E70-E88Compare E86.1 vs E34.5 →
- congenital adrenal hyperplasia (E25.0) inherited from E70-E88Compare E86.1 vs E25.0 →
- hemolytic anemias attributable to enzyme disorders (D55.-) inherited from E70-E88Compare E86.1 vs D55 →
- Marfan syndrome (Q87.4-) inherited from E70-E88Compare E86.1 vs Q87.4 →
- 5-alpha-reductase deficiency (E29.1) inherited from E70-E88Compare E86.1 vs E29.1 →
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- hypovolemic shock NOS (R57.1) inherited from E86Compare E86.1 vs R57.1 →
- Ehlers-Danlos syndromes (Q79.6-) inherited from E70-E88Compare E86.1 vs Q79.6 →
Use Additional Code
Supplementary codes the tabular list directs you to add.
- Use additional code(s) for any associated disorders of electrolyte and acid-base balance (E87.-)
Source: inherited from E86
Coder workflow for E86.1
MedCoder structured workflow — derived from this code’s own official record
Before you code E86.1
- Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with E86.1. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
Choose the right path
- Does the documentation support a condition named in E86.1’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue.
Consider E86.1. Then work the Use Additional Code note, and confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
- The conditions the Use Additional Code note names
- Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.
Official instructions as workflow
Excludes1 — check before selecting E86.1(8 notes)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with E86.1: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
CompareP74.1, T81.19, T79.4, E34.5, E25.0, D55
See the official tabular notes · Guidelines I.A.12.a
Excludes2 — not part of E86.1(2 notes)
Coding workflow: The conditions named in this note are not included in E86.1. When the record documents both, both may be reported; the note is a boundary, not a prohibition.
See the official tabular notes · Guidelines I.A.12.b
Use Additional Code — after identifying E86.1(1 note)
Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with E86.1 when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.
ReviewE87
See the official tabular notes · Guidelines I.A.13
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: Both the condition E86.1 describes and a condition named in its Excludes1 note are documented for the same encounter.
Coding question: Can both codes be reported?
Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.
Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).
Documentation: A condition the Use Additional Code note names is documented.
Coding question: Is a second code reported with E86.1?
Path: Review the Use Additional Code note and the code it names.
Reason: The additional code is reported when the record documents the condition; a conditional instruction applies only when its condition is met (Guidelines I.A.13).
ReviewE87
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Indexed Clinical Terms (2)
Official source data — entries quoted as published, in the Index’s own lookup phrasing
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.
Decision Points
The directives on this code's own record, as a pre-claim checklist.
- 1 Use Additional Code instruction — report the named additional code(s) when the documentation supports them. See the Use Additional Code notes
- 8 Excludes1 entries — codes named there are generally not reported together with this code (Guidelines I.A.12.a). See the Excludes1 notes
- 2 Excludes2 entries — those conditions are not part of this code and may be reported additionally when documented. See the Excludes2 notes
Checklist rows are derived from this code's own official directives; the wording of each check is MedCoder editorial. The official notes themselves are in the sections each row links to.
Verify Before Coding
- No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name E86.1 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 1 Excludes1 note: P59 — Neonatal jaundice from other and unspecified causes (via E86.-).
These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.
Referenced by 15 Excludes2 notes across 4 chapters: G11 — Hereditary ataxia (via E86.-), G71 — Primary disorders of muscles (via E86.-), N25.0 — Renal osteodystrophy (via E86.-), N25.81 — Secondary hyperparathyroidism of renal origin (via E86.-), R79.1 — Abnormal coagulation profile (via E86.-), T80 — Complications following infusion, transfusion and therapeutic injection (via E86.-), T80-T88 — Complications of surgical and medical care, not elsewhere classified (T80-T88) (via E86.-), T81 — Complications of procedures, not elsewhere classified (via E86.-), T82 — Complications of cardiac and vascular prosthetic devices, implants and grafts (via E86.-), T83 — Complications of genitourinary prosthetic devices, implants and grafts (via E86.-), T84 — Complications of internal orthopedic prosthetic devices, implants and grafts (via E86.-), T85 — Complications of other internal prosthetic devices, implants and grafts (via E86.-), T86 — Complications of transplanted organs and tissue (via E86.-), T87 — Complications peculiar to reattachment and amputation (via E86.-), T88 — Other complications of surgical and medical care, not elsewhere classified (via E86.-).
These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.
Referenced by 2 Code First instructions across 2 chapters: G63 — Polyneuropathy in diseases classified elsewhere (via E86.-), H42 — Glaucoma in diseases classified elsewhere (via E86.-).
Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.
MS-DRG Grouper Relationships (FY2026)
Potential MS-DRG participation — not a DRG assignment.
FY2026 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.
Named in the grouper logic of 4 MS-DRGs: DRG 640 (MDC 10), DRG 641 (MDC 10), DRG 791 (MDC 15), DRG 793 (MDC 15).
From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.
Clinical classification (AHRQ CCSR):END011 — Fluid and electrolyte disorders (default).
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Related Codes
Same clinical category (CCSR)
AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Fluid and electrolyte disorders).
E86.0 — Dehydration, E86.9 — Volume depletion, unspecified, E87.0 — Hyperosmolality and hypernatremia, E87.1 — Hypo-osmolality and hyponatremia, E87.2 — Acidosis, E87.20 — Acidosis, unspecified, E87.21 — Acute metabolic acidosis, E87.22 — Chronic metabolic acidosis, E87.29 — Other acidosis, E87.3 — Alkalosis, E87.4 — Mixed disorder of acid-base balance, E87.5 — Hyperkalemia, E87.6 — Hypokalemia, E87.70 — Fluid overload, unspecified, E87.71 — Transfusion associated circulatory overload, E87.79 — Other fluid overload, E87.8 — Other disorders of electrolyte and fluid balance, not elsewhere classified
Same Index main term, other category
The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Depletion”, “Hypovolemia”; these codes share that main term but sit in a different category of the Tabular List.
E87.1 — Hypo-osmolality and hyponatremia (salt or sodium), E87.6 — Hypokalemia (potassium), N25.89 — Other disorders resulting from impaired renal tubular function (potassium, nephropathy), N28.9 — Disorder of kidney and ureter, unspecified (salt or sodium, nephropathy), T67.4 — Heat exhaustion due to salt depletion (salt or sodium, causing heat exhaustion or prostration), T79.4 — Traumatic shock (traumatic), T81.19 — Other postprocedural shock (surgical shock)
Lab tests where this diagnosis supports Medicare coverage (NCD)
Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.
Contextual Map
Every relationship of E86.1 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run E86.1 with these 11 related codes in Claim Check
Hierarchy
- E00-E89 — Chapter 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89) (E00-E89)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E70-E88 — Metabolic disorders[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Referenced by Excludes1 notes
- P59 — Neonatal jaundice from other and unspecified causes[Excludes1](via E86.-): “jaundice due to inborn errors of metabolism (E70-E88)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Excludes2 notes (15)
- G11 — Hereditary ataxia[Excludes2](via E86.-): “metabolic disorders (E70-E88)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- G71 — Primary disorders of muscles[Excludes2](via E86.-): “metabolic disorders (E70-E88)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- N25.0 — Renal osteodystrophy[Excludes2](via E86.-): “metabolic disorders classifiable to E70-E88”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- N25.81 — Secondary hyperparathyroidism of renal origin[Excludes2](via E86.-): “metabolic disorders classifiable to E70-E88”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R79.1 — Abnormal coagulation profile[Excludes2](via E86.-): “abnormality of fluid, electrolyte or acid-base balance (E86-E87)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T80 — Complications following infusion, transfusion and therapeutic injection[Excludes2](via E86.-): “disorders of fluid and electrolyte imbalance (E86-E87)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T80-T88 — Complications of surgical and medical care, not elsewhere classified (T80-T88)[Excludes2](via E86.-): “disorders of fluid and electrolyte imbalance (E86-E87)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T81 — Complications of procedures, not elsewhere classified[Excludes2](via E86.-): “disorders of fluid and electrolyte imbalance (E86-E87)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 7 more
Referenced by Code First instructions
- G63 — Polyneuropathy in diseases classified elsewhere[Code First](via E86.-): “metabolic diseases (E70-E88)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- H42 — Glaucoma in diseases classified elsewhere[Code First](via E86.-): “specified metabolic disorder (E70-E88)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Clinical classification (CCSR)
- END011 — Fluid and electrolyte disorders[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)
MS-DRG Grouper
- DRG 640 — MISCELLANEOUS DISORDERS OF NUTRITION, METABOLISM, FLUIDS AND ELECTROLYTES WITH MCC[MS-DRG]: “MISCELLANEOUS DISORDERS OF NUTRITION, METABOLISM, FLUIDS AND ELECTROLYTES WITH MCC (MDC 10)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
- DRG 641 — MISCELLANEOUS DISORDERS OF NUTRITION, METABOLISM, FLUIDS AND ELECTROLYTES WITHOUT MCC[MS-DRG]: “MISCELLANEOUS DISORDERS OF NUTRITION, METABOLISM, FLUIDS AND ELECTROLYTES WITHOUT MCC (MDC 10)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
- DRG 791 — PREMATURITY WITH MAJOR PROBLEMS[MS-DRG]: “PREMATURITY WITH MAJOR PROBLEMS (MDC 15)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
- DRG 793 — FULL TERM NEONATE WITH MAJOR PROBLEMS[MS-DRG]: “FULL TERM NEONATE WITH MAJOR PROBLEMS (MDC 15)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
MDC crossing
- MDC 10 — Endocrine, Nutritional and Metabolic Diseases and Disorders[MDC crossing]: “Endocrine, Nutritional and Metabolic Diseases and Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 5,008 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026
- MDC 15 — Newborns and Other Neonates with Conditions Originating in Perinatal Period[MDC crossing]: “Newborns and Other Neonates with Conditions Originating in Perinatal Period — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2026
Index entries
- Depletion, plasma[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
- Hypovolemia[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
Nearest codes
- E86 — Volume depletion[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E86.0 — Dehydration[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E86.9 — Volume depletion, unspecified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Inpatient payment groups Official source data
- CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionHypovolemia
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to E86.1 in its code family, with their registry titles.