E34.5 ICD-10-CM Code: Androgen insensitivity syndrome
Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.
Coding at a Glance
- Tabular directives
- 3 Excludes1
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for E34.5 in the official ICD-10-CM tabular list, quoted as published.
Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025
Notes without a marker are published on E34.5 itself; “inherited from” names the category or block whose note applies here.
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- pseudohypoparathyroidism (E20.1) inherited from E34Compare E34.5 vs E20.1 →
- galactorrhea (N64.3) inherited from E20-E35Compare E34.5 vs N64.3 →
- gynecomastia (N62) inherited from E20-E35Compare E34.5 vs N62 →
Coder workflow for E34.5
MedCoder structured workflow — derived from this code’s own official record
Before you code E34.5
- E34.5 is not reportable as written. Select the more specific code beneath it that the documentation supports. Codes are reported to the highest level of specificity the classification provides (Guidelines I.B.2).
See the relationships section · Guide: How to choose an ICD-10-CM code →
- Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with E34.5. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
Choose the right path
- Does the documentation support one of the more specific codes beneath E34.5?
Yes → Select that code and continue the checks below on its own page.
No → E34.5 cannot be reported as written; query for the specificity its subcategory needs. - Does the documentation support a condition named in E34.5’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue.
Consider E34.5. Then confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Official instructions as workflow
Excludes1 — check before selecting E34.5(3 notes)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with E34.5: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
See the official tabular notes · Guidelines I.A.12.a
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: Both the condition E34.5 describes and a condition named in its Excludes1 note are documented for the same encounter.
Coding question: Can both codes be reported?
Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.
Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Verify Before Coding
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name E34.5 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 27 Excludes1 notes across 2 chapters: E29 — Testicular dysfunction, E70 — Disorders of aromatic amino-acid metabolism, E70-E88 — Metabolic disorders (E70-E88), E71 — Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism, E72 — Other disorders of amino-acid metabolism, E73 — Lactose intolerance, E74 — Other disorders of carbohydrate metabolism, E75 — Disorders of sphingolipid metabolism and other lipid storage disorders, E76 — Disorders of glycosaminoglycan metabolism, E77 — Disorders of glycoprotein metabolism, E78 — Disorders of lipoprotein metabolism and other lipidemias, E79 — Disorders of purine and pyrimidine metabolism, E80 — Disorders of porphyrin and bilirubin metabolism, E83 — Disorders of mineral metabolism, E84 — Cystic fibrosis, E85 — Amyloidosis, E86 — Volume depletion, E87 — Other disorders of fluid, electrolyte and acid-base balance, E88 — Other and unspecified metabolic disorders, Q50 — Congenital malformations of ovaries, fallopian tubes and broad ligaments, +7 more.
These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.
Referenced by 1 Code First instruction: G63 — Polyneuropathy in diseases classified elsewhere (via E34.-).
Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.
Contextual Map
Every relationship of E34.5 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run E34.5 with these 9 related codes in Claim Check
Hierarchy
- E00-E89 — Chapter 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89) (E00-E89)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E20-E35 — Disorders of other endocrine glands[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Referenced by Excludes1 notes (27)
- E29 — Testicular dysfunction[Excludes1]: “androgen insensitivity syndrome (E34.5-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E70 — Disorders of aromatic amino-acid metabolism[Excludes1]: “androgen insensitivity syndrome (E34.5-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E70-E88 — Metabolic disorders (E70-E88)[Excludes1]: “androgen insensitivity syndrome (E34.5-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E71 — Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism[Excludes1]: “androgen insensitivity syndrome (E34.5-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E72 — Other disorders of amino-acid metabolism[Excludes1]: “androgen insensitivity syndrome (E34.5-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E73 — Lactose intolerance[Excludes1]: “androgen insensitivity syndrome (E34.5-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E74 — Other disorders of carbohydrate metabolism[Excludes1]: “androgen insensitivity syndrome (E34.5-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E75 — Disorders of sphingolipid metabolism and other lipid storage disorders[Excludes1]: “androgen insensitivity syndrome (E34.5-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 19 more
Referenced by Code First instructions
- G63 — Polyneuropathy in diseases classified elsewhere[Code First](via E34.-): “endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Nearest codes (22)
- E34 — Other endocrine disorders[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E34.0 — Carcinoid syndrome[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E34.00 — Carcinoid syndrome, unspecified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E34.01 — Carcinoid heart syndrome[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E34.09 — Other carcinoid syndrome[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E34.1 — Other hypersecretion of intestinal hormones[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E34.2 — Ectopic hormone secretion, not elsewhere classified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E34.3 — Short stature due to endocrine disorder[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- and 14 more
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Common coding questions
Can E34.5 be billed directly?
No. E34.5 (Androgen insensitivity syndrome) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "E34.5 — Androgen insensitivity syndrome." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/e34.5-androgen-insensitivity-syndrome
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionAndrogen insensitivity syndrome
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to E34.5 in its code family, with their registry titles.
- E34.322 — Insulin-like growth factor-1 (IGF-1) resistance
- E34.328 — Other genetic causes of short stature
- E34.329 — Unspecified genetic causes of short stature
- E34.39 — Other short stature due to endocrine disorder
- E34.4 — Constitutional tall stature
- E34.50 — Androgen insensitivity syndrome, unspecified
- E34.51 — Complete androgen insensitivity syndrome
- E34.52 — Partial androgen insensitivity syndrome
- E34.8 — Other specified endocrine disorders
- E34.9 — Endocrine disorder, unspecified