Z79.810 is the authoritative medical code for Long term current use of selective estrogen receptor modulators SERMs. This classification is used in medical billing and clinical recording to specify the clinical criteria for long term current use of selective estrogen receptor modulators serms (ICD-10-CM Z79.810), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Official Registry Overview & Definition
Long term current use of selective estrogen receptor modulators SERMs is a billable ICD-10-CM diagnosis code Z79.810. Includes: long term current drug use for prophylactic purposes. Inclusion terms: Long term current use of raloxifene Evista; Long term current use of tamoxifen Nolvadex; Long term current use of toremifene Fareston. Excludes1 (not coded here): hormone replacement therapy Z79.890. Excludes2 (not included here): drug abuse and dependence F11-F19; drug use complicating pregnancy, childbirth, and the puerperium O99.32-. Code first: , if applicable:; malignant neoplasm of breast C50.-; malignant neoplasm of prostate C61. Use additional code: code, if applicable, to identify:; estrogen receptor positive status Z17.0; family history of breast cancer Z80.3; genetic susceptibility to malignant neoplasm cancer Z15.0-; personal history of breast cancer Z85.3; personal history of prostate cancer Z85.46; postmenopausal status Z78.0. Code also: any therapeutic drug level monitoring Z51.81; any follow-up examination Z08-Z09.
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for Z79.810 in the official ICD-10-CM tabular list.
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- long term current drug use for prophylactic purposes
Inclusion Terms
Alternative terms the tabular list files under this code.
- Long term current use of raloxifene Evista
- Long term current use of tamoxifen Nolvadex
- Long term current use of toremifene Fareston
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- hormone replacement therapy Z79.890
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- drug abuse and dependence F11-F19
- drug use complicating pregnancy, childbirth, and the puerperium O99.32-
Code First
Underlying conditions that must be sequenced before this code.
- , if applicable:
- malignant neoplasm of breast C50.-
- malignant neoplasm of prostate C61
Code Also
Additional codes that may be required to fully describe the encounter.
- any therapeutic drug level monitoring Z51.81
- any follow-up examination Z08-Z09
Use Additional Code
Supplementary codes the tabular list directs you to add.
- code, if applicable, to identify:
- estrogen receptor positive status Z17.0
- family history of breast cancer Z80.3
- genetic susceptibility to malignant neoplasm cancer Z15.0-
- personal history of breast cancer Z85.3
- personal history of prostate cancer Z85.46
- postmenopausal status Z78.0
Frequently Asked Questions (FAQ) & Clinical Guidance
What can't be coded together with Z79.810?
Per Excludes1 instructions, Z79.810 must not be reported with: hormone replacement therapy (Z79.890).
Can Z79.810 be reported alongside related conditions?
Per Excludes2 instructions, Z79.810 and the following may both be reported when both are present: drug abuse and dependence (F11-F19); drug use complicating pregnancy, childbirth, and the puerperium (O99.32-).
Does Z79.810 need to be sequenced after another code?
Yes. Code first: , if applicable:; malignant neoplasm of breast (C50.-); malignant neoplasm of prostate (C61).
Is an additional code needed with Z79.810?
Use additional code(s) to specify: code, if applicable, to identify:; estrogen receptor positive status (Z17.0); family history of breast cancer (Z80.3); genetic susceptibility to malignant neoplasm (cancer) (Z15.0-).
What conditions are included under Z79.810?
Long term current use of selective estrogen receptor modulators SERMs includes: Long term (current) use of raloxifene (Evista); Long term (current) use of tamoxifen (Nolvadex); Long term (current) use of toremifene (Fareston).
Codes in This Family (40)
Official ICD-10-CM classifications in the same code family as Z79.810, with their registry titles.
- Z79 — Long term (current) drug therapy
- Z79.0 — Long term (current) use of anticoagulants and antithrombotics/antiplatelets
- Z79.01 — Long term (current) use of anticoagulants
- Z79.02 — Long term (current) use of antithrombotics/antiplatelets
- Z79.1 — Long term (current) use of non-steroidal anti-inflammatories (NSAID)
- Z79.2 — Long term (current) use of antibiotics
- Z79.3 — Long term (current) use of hormonal contraceptives
- Z79.4 — Long term (current) use of insulin
- Z79.5 — Long term (current) use of steroids
- Z79.51 — Long term (current) use of inhaled steroids
- Z79.52 — Long term (current) use of systemic steroids
- Z79.6 — Long term (current) use of immunomodulators and immunosuppressants
- Z79.60 — Long term (current) use of unspecified immunomodulators and immunosuppressants
- Z79.61 — Long term (current) use of immunomodulator
- Z79.62 — Long term (current) use of immunosuppressant
- Z79.620 — Long term (current) use of immunosuppressive biologic
- Z79.621 — Long term (current) use of calcineurin inhibitor
- Z79.622 — Long term (current) use of Janus kinase inhibitor
- Z79.623 — Long term (current) use of mammalian target of rapamycin (mTOR) inhibitor
- Z79.624 — Long term (current) use of inhibitors of nucleotide synthesis
- Z79.63 — Long term (current) use of chemotherapeutic agent
- Z79.630 — Long term (current) use of alkylating agent
- Z79.631 — Long term (current) use of antimetabolite agent
- Z79.632 — Long term (current) use of antitumor antibiotic
- Z79.633 — Long term (current) use of mitotic inhibitor
- Z79.634 — Long term (current) use of topoisomerase inhibitor
- Z79.64 — Long term (current) use of myelosuppressive agent
- Z79.69 — Long term (current) use of other immunomodulators and immunosuppressants
- Z79.8 — Other long term (current) drug therapy
- Z79.81 — Long term (current) use of agents affecting estrogen receptors and estrogen levels
- Z79.811 — Long term (current) use of aromatase inhibitors
- Z79.818 — Long term (current) use of other agents affecting estrogen receptors and estrogen levels
- Z79.82 — Long term (current) use of aspirin
- Z79.83 — Long term (current) use of bisphosphonates
- Z79.84 — Long term (current) use of oral hypoglycemic drugs
- Z79.85 — Long-term (current) use of injectable non-insulin antidiabetic drugs
- Z79.89 — Other long term (current) drug therapy
- Z79.890 — Hormone replacement therapy
- Z79.891 — Long term (current) use of opiate analgesic
- Z79.899 — Other long term (current) drug therapy
Indexed Clinical Terms (14)
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.
- Long-term (current) (prophylactic) drug therapy (use of), Evista
- Long-term (current) (prophylactic) drug therapy (use of), Fareston
- Long-term (current) (prophylactic) drug therapy (use of), Nolvadex
- Long-term (current) (prophylactic) drug therapy (use of), raloxifene (Evista)
- Long-term (current) (prophylactic) drug therapy (use of), selective estrogen receptor modulators (SERMs)
- Long-term (current) (prophylactic) drug therapy (use of), tamoxifen (Nolvadex)
- Long-term (current) (prophylactic) drug therapy (use of), toremifene (Fareston)
- Therapy, drug, long-term (current) (prophylactic), Evista
- Therapy, drug, long-term (current) (prophylactic), Fareston
- Therapy, drug, long-term (current) (prophylactic), Nolvadex
- Therapy, drug, long-term (current) (prophylactic), raloxifene (Evista)
- Therapy, drug, long-term (current) (prophylactic), selective estrogen receptor modulators (SERMs)
- Therapy, drug, long-term (current) (prophylactic), tamoxifen (Nolvadex)
- Therapy, drug, long-term (current) (prophylactic), toremifene (Fareston)
Related Codes & Numerical Sequence (Crawl Map)
Search engines and indexers are advised to traverse adjacent medical codes in this sub-chapter range to find correlated diagnoses or therapeutic procedures: