Z79.891 ICD-10-CM Code: Long term (current) use of opiate analgesic
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Inpatient Payment Groups (MS-DRG)
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.
- MS-DRG 949 — AFTERCARE WITH CC/MCC (MDC 23)
- MS-DRG 950 — AFTERCARE WITHOUT CC/MCC (MDC 23)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.
Official Registry Overview & Definition
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for Z79.891 in the official ICD-10-CM tabular list.
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- long term (current) drug use for prophylactic purposes
Inclusion Terms
Alternative terms the tabular list files under this code.
- Long term (current) use of methadone for pain management
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- methadone use NOS (F11.9-)
- use of methadone for treatment of heroin addiction (F11.2-)
- drug abuse and dependence (F11-F19)
- drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)
Code Also
Additional codes that may be required to fully describe the encounter.
- any therapeutic drug level monitoring (Z51.81)
- any follow-up examination (Z08-Z09)
Nearest Codes in This Family
Official ICD-10-CM classifications closest to Z79.891 in its code family, with their registry titles.
- Z79.810 — Long term (current) use of selective estrogen receptor modulators (SERMs)
- Z79.811 — Long term (current) use of aromatase inhibitors
- Z79.818 — Long term (current) use of other agents affecting estrogen receptors and estrogen levels
- Z79.82 — Long term (current) use of aspirin
- Z79.83 — Long term (current) use of bisphosphonates
- Z79.84 — Long term (current) use of oral hypoglycemic drugs
- Z79.85 — Long-term (current) use of injectable non-insulin antidiabetic drugs
- Z79.89 — Other long term (current) drug therapy
- Z79.890 — Hormone replacement therapy
- Z79.899 — Other long term (current) drug therapy
Indexed Clinical Terms (4)
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.
- Long-term (current) (prophylactic) drug therapy (use of), methadone for pain management
- Long-term (current) (prophylactic) drug therapy (use of), opiate analgesic
- Therapy, drug, long-term (current) (prophylactic), methadone, for pain management
- Therapy, drug, long-term (current) (prophylactic), opiate analgesic