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ICD-10/Z85.46

Z85.46 ICD-10-CM Code: Personal history of malignant neoplasm of prostate

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.

  • MS-DRG 826 — MYELOPROLIFERATIVE DISORDERS OR POORLY DIFFERENTIATED NEOPLASMS WITH MAJOR O.R. PROCEDURES WITH MCC (MDC 17)
  • MS-DRG 827 — MYELOPROLIFERATIVE DISORDERS OR POORLY DIFFERENTIATED NEOPLASMS WITH MAJOR O.R. PROCEDURES WITH CC (MDC 17)
  • MS-DRG 828 — MYELOPROLIFERATIVE DISORDERS OR POORLY DIFFERENTIATED NEOPLASMS WITH MAJOR O.R. PROCEDURES WITHOUT CC/MCC (MDC 17)
  • MS-DRG 829 — MYELOPROLIFERATIVE DISORDERS OR POORLY DIFFERENTIATED NEOPLASMS WITH OTHER PROCEDURES WITH CC/MCC (MDC 17)
  • MS-DRG 830 — MYELOPROLIFERATIVE DISORDERS OR POORLY DIFFERENTIATED NEOPLASMS WITH OTHER PROCEDURES WITHOUT CC/MCC (MDC 17)
  • MS-DRG 843 — OTHER MYELOPROLIFERATIVE DISORDERS OR POORLY DIFFERENTIATED NEOPLASTIC DIAGNOSES WITH MCC (MDC 17)
  • MS-DRG 844 — OTHER MYELOPROLIFERATIVE DISORDERS OR POORLY DIFFERENTIATED NEOPLASTIC DIAGNOSES WITH CC (MDC 17)
  • MS-DRG 845 — OTHER MYELOPROLIFERATIVE DISORDERS OR POORLY DIFFERENTIATED NEOPLASTIC DIAGNOSES WITHOUT CC/MCC (MDC 17)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.

Official Registry Overview & Definition

Personal history of malignant neoplasm of prostate is a billable ICD-10-CM diagnosis code (Z85.46).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for Z85.46 in the official ICD-10-CM tabular list.

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

  • personal history of benign neoplasm (Z86.01-)
  • personal history of carcinoma-in-situ (Z86.00-)

Code First

Underlying conditions that must be sequenced before this code.

  • any follow-up examination after treatment of malignant neoplasm (Z08)

Code Also

Additional codes that may be required to fully describe the encounter.

  • any follow-up examination (Z08-Z09)

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code to identify:
  • alcohol use and dependence (F10.-)
  • exposure to environmental tobacco smoke (Z77.22)
  • history of tobacco dependence (Z87.891)
  • occupational exposure to environmental tobacco smoke (Z57.31)
  • tobacco dependence (F17.-)
  • tobacco use (Z72.0)

Nearest Codes in This Family

Official ICD-10-CM classifications closest to Z85.46 in its code family, with their registry titles.

  • Z85.41 — Personal history of malignant neoplasm of cervix uteri
  • Z85.42 — Personal history of malignant neoplasm of other parts of uterus
  • Z85.43 — Personal history of malignant neoplasm of ovary
  • Z85.44 — Personal history of malignant neoplasm of other female genital organs
  • Z85.45 — Personal history of malignant neoplasm of unspecified male genital organ
  • Z85.47 — Personal history of malignant neoplasm of testis
  • Z85.48 — Personal history of malignant neoplasm of epididymis
  • Z85.49 — Personal history of malignant neoplasm of other male genital organs
  • Z85.4A — Personal history of malignant neoplasm of fallopian tube(s)
  • Z85.5 — Personal history of malignant neoplasm of urinary tract

View all codes in the Z85 family

Indexed Clinical Terms (1)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • History, personal (of), malignant neoplasm (of), prostate