00PE43Z ICD-10-PCS Code: Removal of Infusion Device from Cranial Nerve, Percutaneous Endoscopic Approach

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

The MS-DRG grouper treats this as an operating room procedure. It appears in the surgical logic of 3 MS-DRGs:

• MDC 01 — Peripheral, Cranial Nerve and Other Nervous System Procedures: DRG 040, DRG 041, DRG 042

From the CMS MS-DRG Definitions Manual, Appendix E. Actual DRG assignment depends on the complete claim.

Related Codes

Same operation — other Body Part

Same table and root operation, differing only in the body part character.

00P043Z — Removal of Infusion Device from Brain, Percutaneous Endoscopic Approach, 00P643Z — Removal of Infusion Device from Cerebral Ventricle, Percutaneous Endoscopic Approach, 00PU43Z — Removal of Infusion Device from Spinal Canal, Percutaneous Endoscopic Approach, 00PV43Z — Removal of Infusion Device from Spinal Cord, Percutaneous Endoscopic Approach

Same operation — other Approach

Same table and root operation, differing only in the approach character.

00PE03Z — Removal of Infusion Device from Cranial Nerve, Open Approach, 00PE33Z — Removal of Infusion Device from Cranial Nerve, Percutaneous Approach, 00PEX3Z — Removal of Infusion Device from Cranial Nerve, External Approach

Same operation — other Device

Same table and root operation, differing only in the device character.

00PE40Z — Removal of Drainage Device from Cranial Nerve, Percutaneous Endoscopic Approach, 00PE42Z — Removal of Monitoring Device from Cranial Nerve, Percutaneous Endoscopic Approach, 00PE47Z — Removal of Autologous Tissue Substitute from Cranial Nerve, Percutaneous Endoscopic Approach, 00PE4MZ — Removal of Neurostimulator Lead from Cranial Nerve, Percutaneous Endoscopic Approach, 00PE4YZ — Removal of Other Device from Cranial Nerve, Percutaneous Endoscopic Approach

Same procedure category (CCSR), other tables

AHRQ's Clinical Classifications Software Refined groups these ICD-10-PCS procedures with this one under CNS procedures, NEC (Central Nervous System Procedures); listed here are the members in other PCS tables. Source: Clinical Classifications Software Refined (CCSR), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, November 2025.

00NP4ZZ — Release Glossopharyngeal Nerve, Percutaneous Endoscopic Approach, 00NQ0ZZ — Release Vagus Nerve, Open Approach, 00NQ3ZZ — Release Vagus Nerve, Percutaneous Approach, 00NQ4ZZ — Release Vagus Nerve, Percutaneous Endoscopic Approach, 00NR0ZZ — Release Accessory Nerve, Open Approach, 00NR3ZZ — Release Accessory Nerve, Percutaneous Approach, 00NR4ZZ — Release Accessory Nerve, Percutaneous Endoscopic Approach, 00NS0ZZ — Release Hypoglossal Nerve, Open Approach, 00NS3ZZ — Release Hypoglossal Nerve, Percutaneous Approach, 00NS4ZZ — Release Hypoglossal Nerve, Percutaneous Endoscopic Approach, 00SF0ZZ — Reposition Olfactory Nerve, Open Approach, 00SF3ZZ — Reposition Olfactory Nerve, Percutaneous Approach, 00SF4ZZ — Reposition Olfactory Nerve, Percutaneous Endoscopic Approach, 00SG0ZZ — Reposition Optic Nerve, Open Approach, 00SG3ZZ — Reposition Optic Nerve, Percutaneous Approach, 00SG4ZZ — Reposition Optic Nerve, Percutaneous Endoscopic Approach, 00SH0ZZ — Reposition Oculomotor Nerve, Open Approach, 00SH3ZZ — Reposition Oculomotor Nerve, Percutaneous Approach, 00SH4ZZ — Reposition Oculomotor Nerve, Percutaneous Endoscopic Approach, 00SJ0ZZ — Reposition Trochlear Nerve, Open Approach, +569 more

Contextual Map

Every relationship of 00PE43Z in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run 00PE43Z with these 5 related codes in Claim Check

PCS table

• 00P[PCS table]— CMS ICD-10-PCS tables
• Medical and Surgical — Section: Medical and Surgical[Section]: “Medical and Surgical”— CMS ICD-10-PCS tables
• Central Nervous System and Cranial Nerves — Body System: Central Nervous System and Cranial Nerves[Body System]: “Central Nervous System and Cranial Nerves”— CMS ICD-10-PCS tables
• Removal — Operation: Removal[Operation]: “Removal”— CMS ICD-10-PCS tables

MS-DRG participation

• DRG 040 — PERIPHERAL, CRANIAL NERVE AND OTHER NERVOUS SYSTEM PROCEDURES WITH MCC[MS-DRG]: “PERIPHERAL, CRANIAL NERVE AND OTHER NERVOUS SYSTEM PROCEDURES WITH MCC — Peripheral, Cranial Nerve and Other Nervous System Procedures (MDC 01)”— CMS MS-DRG Definitions Manual (Appendix E) · FY2026
• DRG 041 — PERIPHERAL, CRANIAL NERVE AND OTHER NERVOUS SYSTEM PROCEDURES WITH CC OR PERIPHERAL NEUROSTIMULATOR[MS-DRG]: “PERIPHERAL, CRANIAL NERVE AND OTHER NERVOUS SYSTEM PROCEDURES WITH CC OR PERIPHERAL NEUROSTIMULATOR — Peripheral, Cranial Nerve and Other Nervous System Procedures (MDC 01)”— CMS MS-DRG Definitions Manual (Appendix E) · FY2026
• DRG 042 — PERIPHERAL, CRANIAL NERVE AND OTHER NERVOUS SYSTEM PROCEDURES WITHOUT CC/MCC[MS-DRG]: “PERIPHERAL, CRANIAL NERVE AND OTHER NERVOUS SYSTEM PROCEDURES WITHOUT CC/MCC — Peripheral, Cranial Nerve and Other Nervous System Procedures (MDC 01)”— CMS MS-DRG Definitions Manual (Appendix E) · FY2026

Clinical classification (CCSR)

• CNS014 — CNS procedures, NEC[CCSR category]: “CNS procedures, NEC — Central Nervous System Procedures”— AHRQ CCSR for ICD-10-PCS Procedures (HCUP) · v2026.1

MDC crossing · diagnoses (2636)

• MDC 01 — Diseases and Disorders of the Nervous System[MDC crossing]: “Diseases and Disorders of the Nervous System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2026
• A02.21 — Salmonella meningitis[Same-MDC diagnosis]: “Salmonella meningitis — grouped in MDC 01, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• A06.6 — Amebic brain abscess[Same-MDC diagnosis]: “Amebic brain abscess — grouped in MDC 01, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• A17.0 — Tuberculous meningitis[Same-MDC diagnosis]: “Tuberculous meningitis — grouped in MDC 01, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• A17.1 — Meningeal tuberculoma[Same-MDC diagnosis]: “Meningeal tuberculoma — grouped in MDC 01, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• A17.81 — Tuberculoma of brain and spinal cord[Same-MDC diagnosis]: “Tuberculoma of brain and spinal cord — grouped in MDC 01, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• and 2631 more

Nearest codes

• 00P043Z — Removal of Infusion Device from Brain, Percutaneous Endoscopic Approach[One axis away]— CMS ICD-10-PCS tables
• 00P643Z — Removal of Infusion Device from Cerebral Ventricle, Percutaneous Endoscopic Approach[One axis away]— CMS ICD-10-PCS tables
• 00PE03Z — Removal of Infusion Device from Cranial Nerve, Open Approach[One axis away]— CMS ICD-10-PCS tables
• 00PE33Z — Removal of Infusion Device from Cranial Nerve, Percutaneous Approach[One axis away]— CMS ICD-10-PCS tables
• 00PE40Z — Removal of Drainage Device from Cranial Nerve, Percutaneous Endoscopic Approach[One axis away]— CMS ICD-10-PCS tables
• 00PE42Z — Removal of Monitoring Device from Cranial Nerve, Percutaneous Endoscopic Approach[One axis away]— CMS ICD-10-PCS tables
• 00PE47Z — Removal of Autologous Tissue Substitute from Cranial Nerve, Percutaneous Endoscopic Approach[One axis away]— CMS ICD-10-PCS tables
• 00PE4MZ — Removal of Neurostimulator Lead from Cranial Nerve, Percutaneous Endoscopic Approach[One axis away]— CMS ICD-10-PCS tables