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Inpatient Procedure Code

X053X4B ICD-10-PCS Code: Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11

Destruc Brain w Focused Ultrasound, Extern, New Tech 11

Axis Breakdown

Every ICD-10-PCS code is exactly seven characters, one per axis. Each character's meaning is defined by its position in the code.

PositionValueMeaning
1
SectionX

New Technology

2
Body System0

Nervous System

3
Root Operation5

Destruction

Physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent

4
Body Part3

Brain

5
ApproachX

External

6
Device / Substance / Technology4

Focused Ultrasound Therapy

7
New Technology GroupB

New Technology Group 11

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

The MS-DRG grouper treats this as an operating room procedure. It appears in the surgical logic of 13 MS-DRGs:

From the CMS MS-DRG Definitions Manual, Appendix E. Actual DRG assignment depends on the complete claim.

Related Codes

Same procedure category (CCSR), other tables

AHRQ's Clinical Classifications Software Refined groups these ICD-10-PCS procedures with this one under CNS excision procedures (Central Nervous System Procedures); listed here are the members in other PCS tables. Source: Clinical Classifications Software Refined (CCSR), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, November 2025.

00DN3ZZ — Extraction of Acoustic Nerve, Percutaneous Approach, 00DN4ZZ — Extraction of Acoustic Nerve, Percutaneous Endoscopic Approach, 00DP0ZZ — Extraction of Glossopharyngeal Nerve, Open Approach, 00DP3ZZ — Extraction of Glossopharyngeal Nerve, Percutaneous Approach, 00DP4ZZ — Extraction of Glossopharyngeal Nerve, Percutaneous Endoscopic Approach, 00DQ0ZZ — Extraction of Vagus Nerve, Open Approach, 00DQ3ZZ — Extraction of Vagus Nerve, Percutaneous Approach, 00DQ4ZZ — Extraction of Vagus Nerve, Percutaneous Endoscopic Approach, 00DR0ZZ — Extraction of Accessory Nerve, Open Approach, 00DR3ZZ — Extraction of Accessory Nerve, Percutaneous Approach, 00DR4ZZ — Extraction of Accessory Nerve, Percutaneous Endoscopic Approach, 00DS0ZZ — Extraction of Hypoglossal Nerve, Open Approach, 00DS3ZZ — Extraction of Hypoglossal Nerve, Percutaneous Approach, 00DS4ZZ — Extraction of Hypoglossal Nerve, Percutaneous Endoscopic Approach, 00DT0ZZ — Extraction of Spinal Meninges, Open Approach, 00DT3ZZ — Extraction of Spinal Meninges, Percutaneous Approach, 00DT4ZZ — Extraction of Spinal Meninges, Percutaneous Endoscopic Approach, 00T70ZZ — Resection of Cerebral Hemisphere, Open Approach, 00T73ZZ — Resection of Cerebral Hemisphere, Percutaneous Approach, 00T74ZZ — Resection of Cerebral Hemisphere, Percutaneous Endoscopic Approach, +236 more

Contextual Map

Every relationship of X053X4B in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run X053X4B with these 5 related codes in Claim Check

PCS table

MS-DRG participation (13)

Clinical classification (CCSR)

  • CNS007 — CNS excision procedures[CCSR category]: “CNS excision procedures — Central Nervous System Procedures”— AHRQ CCSR for ICD-10-PCS Procedures (HCUP) · v2026.1

MDC crossing · diagnoses (3301)

  • MDC 01 — Diseases and Disorders of the Nervous System[MDC crossing]: “Diseases and Disorders of the Nervous System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2026
  • MDC 17 — Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms[MDC crossing]: “Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2026
  • A02.21 — Salmonella meningitis[Same-MDC diagnosis]: “Salmonella meningitis — grouped in MDC 01, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • A06.6 — Amebic brain abscess[Same-MDC diagnosis]: “Amebic brain abscess — grouped in MDC 01, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • A17.0 — Tuberculous meningitis[Same-MDC diagnosis]: “Tuberculous meningitis — grouped in MDC 01, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • A17.1 — Meningeal tuberculoma[Same-MDC diagnosis]: “Meningeal tuberculoma — grouped in MDC 01, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • A17.81 — Tuberculoma of brain and spinal cord[Same-MDC diagnosis]: “Tuberculoma of brain and spinal cord — grouped in MDC 01, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • and 3296 more

Change history

No changes recorded for this code. This ledger tracks additions, deletions and description changes from FY2026 (April) onward. Note changes are not tracked.

Read from: CMS ICD-10-PCS code tables, index and definitions — FY2026 (April); CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43; AHRQ HCUP Clinical Classifications Software Refined for ICD-10-PCS Procedures (hcup-us.ahrq.gov/toolssoftware/ccsr/PRCCSR_v2026-1.zip) — v2026.1. All data sources · How to read the labels