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Labs/Hemoglobin A1C (HbA1c) Test
Clinical Test & Procedure Reference

Hemoglobin A1C (HbA1c) Test

A hemoglobin A1C (HbA1C) test is a blood test that shows your average level of blood glucose , also called blood sugar, over the past two to three months.

A hemoglobin A1C (HbA1C) test is a blood test that shows your average level of blood glucose , also called blood sugar, over the past two to three months. Glucose is a type of sugar in your blood that comes from the foods you eat. Your cells use glucose for energy. A hormone called insulin helps glucose get into your cells. If you have diabetes your body doesn't make enough insulin, or your cells don't use it well. As a result, glucose can't get into your cells, so your blood glucose levels increase. Glucose in your blood sticks to hemoglobin, a protein in your red blood cells. As your blood glucose levels increase, more of your hemoglobin will be coated with glucose. An A1C test measures the percentage of your red blood cells that have glucose-coated hemoglobin. An A1C test can show your average glucose level for the past three months because: Glucose sticks to hemoglobin for as long as the red blood cells are alive. Red blood cells live about three months. High A1C levels are a sign of high blood glucose from diabetes. Diabetes can cause serious health problems , including heart disease , kidney disease , and nerve damage . But with treatment and lifestyle changes, you can control your blood glucose levels. Other names: HbA1C, A1C, glycohemoglobin, glycated hemoglobin, glycosylated hemoglobin

Why is this test ordered? The Centers for Disease Control (CDC) recommends A1C testing for diabetes and prediabetes if: You are over age 45. If your results are normal, your provider will tell you how often you should be tested based on your age and risk factors. If your results show you have prediabetes, you will usually need to be tested every 1 to 2 years. Ask your provider how often to get tested and what you can do to reduce your risk of developing diabetes. If your results show you have diabetes, you should get an A1C test at least twice a year to monitor your condition and treatment. You are under 45 and are more likely to develop diabetes because you: Have prediabetes. Are overweight or have obesity . Have a parent or sibling with type 2 diabetes. Have high blood pressure or high cholesterol levels. Have heart disease or have had a stroke . Are physically active less than 3 times a week. Have had gestational diabetes (diabetes during pregnancy) or given birth to a baby over 9 pounds. Are African American, Hispanic or Latino, American Indian, or an Alaska Native person. Some Pacific Islander and Asian American people also have a higher risk of developing diabetes. Have polycystic ovarian syndrome (PCOS). You may also need an A1C test if you have symptoms of diabetes, such as: Feeling very thirsty Urinating (peeing) a lot Losing weight without trying Feeling very hungry Blurred vision Numb or tingling hands or feet Fatigue Dry skin Sores that heal slowly Having more infections than usual

Clinical Interpretation

A1C results tell you what percentage of your hemoglobin is coated with glucose. The ranges are just a guide to what is normal. What's normal for you depends on your health, age, and other factors. Ask your provider what A1C percentage is healthy for you. To diagnose diabetes or prediabetes, the percentages commonly used are: Normal: A1C below 5.7% Prediabetes: A1C between 5.7% and 6.4% Diabetes: A1C of 6.5% or higher Providers often use more than one test to diagnose diabetes. So, if your test result was higher than normal, you may have another A1C test or a different type of diabetes test , usually either a fasting blood glucose test or an oral glucose tolerance test (OGTT). If your A1C test was done to monitor your diabetes, talk with your provider about what your test results mean. Learn more about laboratory tests, reference ranges, and understanding results .

Clinical Protocol & Patient Advice

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    Certain medicines such as opioids and some HIV medicines may affect your results, so tell your provider about everything you take. But don't stop taking any medicines unless your provider tells you to. Also, let your health care provider know if you are pregnant, since this may affect your results.

Usage Guidance

  • Reference ranges vary by laboratory. Always discuss your specific results with a qualified healthcare professional.

Source: MedlinePlus, National Library of Medicine. View the original.