Hepatitis Testing
Generally, hepatitis testing is used to find out if there is any sign of hepatitis in your blood.
Generally, hepatitis testing is used to find out if there is any sign of hepatitis in your blood. For hepatitis A, B, D, and E, a test can tell the difference between a present and a past infection. For hepatitis C, however, a test can't tell the difference between an active infection and a past infection that has cleared up. If testing shows that you may have hepatitis, you'll usually need other tests to confirm the diagnosis and to find out whether your infection is acute (sudden) or chronic (long-term).
Why is this test ordered? You may need hepatitis testing if you have symptoms of hepatitis. Hepatitis doesn't always cause symptoms, but when it does, they may include: Jaundice , a condition that causes your skin and eyes to turn yellow. Fever . Fatigue . Loss of appetite. Dark-colored urine. Pale or clay-colored stool (poop). Abdominal (belly) pain. Nausea and vomiting . Joint pain. Diarrhea (hepatitis A only). If left untreated, a hepatitis infection can become chronic (long-term). These kinds of infections can lead to serious liver problems such as cirrhosis or liver cancer . Because of this, your provider may order hepatitis testing if you've had liver function tests with abnormal results. Even if you don't have symptoms, your provider may order a hepatitis test if you've been exposed to a specific hepatitis virus, or if you're at high risk of getting an infection. You may be at high risk if you: Work in certain industries, such as health care. Use illegal intravenous (IV) drugs and/or share needles with others. Have certain medical conditions that weaken your immune system, such as HIV . Have other kinds of liver disease. Are a man who has sex with other men. Already have another hepatitis infection. For example, your provider may test for hepatitis D if you already have hepatitis B. Lastly, your provider may test you for hepatitis as part of a more general health screening. Medical experts recommend that all adults aged 18 and older be tested for hepatitis B and/or C at least once in their lifetime. They also recommend HBV and HCV tests during each pregnancy as part of routine prenatal testing .
Clinical Interpretation
Different labs report hepatitis test results in various ways, so it's best to ask your provider what your test results mean. In general: A negative or normal result means you probably don't have a hepatitis infection. But if you know you were exposed to hepatitis, you may need to be tested again later on. A positive or abnormal result may mean: You have an active hepatitis infection now. It may be an acute infection or one you've had for a long time. You had a hepatitis infection in the past that cleared up. An abnormal test result means that signs of hepatitis were found in your blood. These signs include: Hepatitis antigens , which are substances in the hepatitis virus that trigger your immune system to fight the virus. If you have hepatitis antigens in your blood, it means that you may have an active hepatitis infection. It could be an acute or chronic infection. Hepatitis antibodies , which are proteins that your immune system makes to help fight a hepatitis infection. If you have hepatitis antibodies in your blood, it may mean that you have an acute or chronic infection or that you had an infection in the past. If your test results are abnormal, you will likely need other tests to find out if you have an active infection and whether it is an acute or chronic infection. For example, if your test results suggest a hepatitis B infection, your provider may use a type of test called a triple panel that checks your blood for: Hepatitis B Surface Antigen (HBsAg) , an antigen on the surface of the hepatitis B virus. Hepatitis B Surface-Antibody (Anti-HBs) , an antibody that your immune system makes to fight HBV after a hepatitis B infection or vaccination. Anti-HBc , another antibody that your immune system makes to fight HBV, but only after a hepatitis B infection. If you have questions about your results, talk with your provider. Learn more about laboratory tests, reference ranges, and understanding results .
Medicare Coverage — diagnoses supporting medical necessity (NCD)
Showing 18 of 187 diagnoses Medicare covers for this test under NCD 190.33. The complete list is in CMS's Lab NCD code list.
Clinical Protocol & Patient Advice
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You don't need any special preparations for hepatitis testing.
Usage Guidance
- Reference ranges vary by laboratory. Always discuss your specific results with a qualified healthcare professional.
Source: MedlinePlus, National Library of Medicine. View the original.
Read from: MedlinePlus (NLM); reference ranges only where NIDDK, NIH ODS or NCI states the value, linked per page — Curated from federal sources. All data sources · How to read the labels