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Labs/MCV (Mean Corpuscular Volume)
Clinical Test & Procedure Reference

MCV (Mean Corpuscular Volume)

MCV stands for mean corpuscular volume.

MCV stands for mean corpuscular volume. An MCV blood test measures the average size of your red blood cells. Red blood cells carry oxygen from your lungs to every cell in your body. Your cells need oxygen to grow, reproduce, and make energy. If your red blood cells are too small or too large, it could be a sign of a blood disorder such as anemia , a lack of certain vitamins, or other medical conditions. Other names: CBC with differential, Mean Cell Volume, Mean Corpuscular Volume

Why is this test ordered? Your health care provider may order a complete blood count, which includes an MCV test, as part of your routine checkup . You may also have the test if you have a chronic (long-lasting) condition that could lead to anemia or if you have symptoms of anemia, which could include: Shortness of breath Weakness or fatigue Headache Dizziness Arrhythmia (a problem with the rate or rhythm of your heartbeat)

Clinical Interpretation

An MCV test alone cannot diagnose any disease. Your provider will use the results of your MCV, other test results, and your medical history to make a diagnosis. If your results show that your red blood cells are smaller than normal , it may be a sign of: Certain types of anemia, including iron deficiency anemia, the most common form of anemia. It happens when you don't have enough iron in your body. Thalassemia , which is a group of blood disorders that are inherited (passed down through families). These disorders cause your body to make fewer healthy red blood cells and less hemoglobin. This can cause severe anemia. If your results show that your red blood cells are larger than normal , it may be a sign of: Pernicious anemia, which may be caused by: A lack of vitamin B12 A disease that affects your body's ability to use vitamin B12, such as certain autoimmune diseases , celiac disease , or Crohn's disease Anemia caused by a lack of folic acid Liver disease It's also possible to have anemia with a normal MCV . This may happen if anemia is caused by conditions, such as: A sudden l oss of blood Kidney failure Aplastic anemia (uncommon) If your MCV levels are not in the normal range, it doesn't always mean you have a medical problem that needs treatment. Your age, diet, activity level, medicines, menstrual period , and other conditions can affect the test results. Talk with your provider to learn what your results mean. Learn more about laboratory tests, reference ranges, and understanding results .

Clinical Protocol & Patient Advice

  • 1

    You don't need any special preparations for an MCV blood test. If your provider has ordered more tests on your blood sample, you may need to fast (not eat or drink) for several hours before the test. Your provider will let you know if there are any special instructions to follow.

Usage Guidance

  • Reference ranges vary by laboratory. Always discuss your specific results with a qualified healthcare professional.

Source: MedlinePlus, National Library of Medicine. View the original.