Urobilinogen in Urine
A urobilinogen in urine test measures the amount of urobilinogen in your urine (pee).
A urobilinogen in urine test measures the amount of urobilinogen in your urine (pee). Urobilinogen comes from bilirubin. Your body makes bilirubin during the normal process of breaking down old red blood cells. Your liver uses the bilirubin to make bile, a fluid that helps you digest food in your intestines. Some bile flows through your bile ducts (small tubes) from your liver directly into your intestines. The rest is stored in your gallbladder for when you need it. Good bacteria in your intestines breaks down the bilirubin in your bile and makes urobilinogen. Some of the urobilinogen leaves your body in your stool (poop). Some of it enters your bloodstream and returns to your liver, where it's "recycled" into bile. Normal urine contains some urobilinogen. High levels of urobilinogen in urine may be a sign that: Your liver can't recycle urobilinogen into bile because of a liver disease such as hepatitis or cirrhosis . Your liver is making too much bilirubin because your body breaks down red blood cells faster than it can make them. This condition is called hemolytic anemia . Little or no urobilinogen in urine may be a sign of: Something blocking bile from flowing into your intestines. Other problems with your liver, gallbladder , or bile ducts . Other names: urine test; urine analysis; UA, chemical urinalysis
Why is this test ordered? Your health care provider may order this test as part of your routine checkup or to monitor an existing liver condition. You may also have this test if you have symptoms of liver disease or hemolytic anemia. Liver disease/damage symptoms may include: Nausea and vomiting Lack of appetite Fatigue Weakness Jaundice , a condition that causes your skin and eyes to turn yellow Swelling and/or pain in your abdomen (belly) Swelling in your ankles and legs Dark-colored urine (pee) and/or light-colored stool (poop) Frequent itching Hemolytic anemia symptoms may include: Fatigue Dizziness Heart palpitations (feeling that your heart is pounding or racing) Headache Problems concentrating or thinking Jaundice Abdominal (belly) pain due to an enlarged liver or spleen
Clinical Interpretation
If your test results show too little or no urobilinogen in your urine, it may be a sign of: A blockage in the ducts that carry bile from your liver or gallbladder to your intestines A blockage in the blood flow through the liver A problem with liver function If your test results show a higher-than-normal level of urobilinogen , it may be a sign of: Hepatitis Cirrhosis Liver damage due to medicines Hemolytic anemia If your test results aren't normal, it doesn't always mean you have a medical condition that needs treatment. Certain medicines and supplements can affect your results, so be sure to let your provider know what you are taking. But don't stop taking any medicines unless your provider tells you to. Learn more about laboratory tests, reference ranges, and understanding results .
Clinical Protocol & Patient Advice
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You don't need any special preparations. If your provider has ordered other urine or blood tests, you may need to fast (not eat or drink) for several hours before the test. Your provider will let you know if there are any special instructions to follow.
Usage Guidance
- Reference ranges vary by laboratory. Always discuss your specific results with a qualified healthcare professional.
Source: MedlinePlus, National Library of Medicine. View the original.