Skip to main content

Alka-Seltzer Plus Severe Sinus Cold and Cough

NDC 0280-0507 · Bayer HealthCare LLC.

Generic nameAcetaminophen, Dextromethorphan hydrobromide, Guaifenesin, Phenylephrine hydrochloride
Dosage formCAPSULE, LIQUID FILLED
RouteORAL
Active ingredient(s)ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, PHENYLEPHRINE HYDROCHLORIDE
Strength250; 10; 200; 5 mg/1; mg/1; mg/1; mg/1
Pharmacologic classAdrenergic alpha1-Agonists [MoA], Decreased Respiratory Secretion Viscosity [PE], Expectorant [EPC], Increased Respiratory Secretions [PE], Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA], alpha-1 Adrenergic Agonist [EPC]
Marketing categoryOTC MONOGRAPH DRUG

Packages

0280-0507-20 — 2 BLISTER PACK in 1 CARTON (0280-0507-20) / 20 CAPSULE, LIQUID FILLED in 1 BLISTER PACK

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

0280-0078 — ACETAMINOPHEN, CAFFEINE, and PYRILAMINE MALEATE, 0280-0088 — chlorpheniramine maleate, acetaminophen, phenylephrine hydrochloride, dextromethorphan hydrobromide, 0280-0089 — dextromethorphan hydrobromide, guaifenesin, 0280-0092 — Acetaminophen, Chlorpheniramine malaeate, Dextromethorphan hydrobromide, Phenylephrine hydrochloride, 0280-0095 — Acetaminophen, Dextromethorphan hydrobromide , Phenylephrine hydrochloride, 0280-0097 — Acetaminophen, Dextromethorphan hydrobromide , Doxylamine Succinate, Phenylephrine hydrochloride, 0280-0121 — aspirin, chlorpheniramine maleate, dextromethorphan hydrobromide, phenylephrine bitartrate, 0280-0151 — chlorpheniramine maleate, acetaminophen, dextromethorphan hydrobromide, 0280-0152 — acetaminophen, dextromethorphan hydrobromide, 0280-0505 — Alka-Seltzer Plus Severe Cough Mucus and Congestion, 0280-0921 — ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE, 0280-0922 — ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, and PHENYLEPHRINE HYDROCHLORIDE, 0280-1545 — Aspirin, Dextromethorphan hydrobromide, Doxylamine succinate, Phenylephrine bitartrate, 0280-1555 — Aspirin, Chlorpheniramine maleate, Dextromethorphan hydrobromide, Phenylephrine bitartrate, 0280-1570 — Acetaminophen, Chlorpheniramine maleate, Dextromethorphan hydrobromide, Phenylephrine hydrochloride, 0280-1590 — Acetaminophen, Dextromethorphan Hydrobromide, Phenylephrine Hydrochloride, 0280-1600 — Acetaminophen, Dextromethorphan hydrobromide, Doxylamine succinate, Phenylephrine hydrochloride, 0280-1620 — Acetaminophen, Dextromethorphan hydrobromide, Doxylamine succinate, Phenylephrine hydrochloride, 0280-1630 — acetaminophen, dextromethorphan hydrobromide, phenylephrine hydrochloride, 0280-1640 — acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, phenylephrine hydrochloride, +5267 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.