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ALKA SELTZER COLD Cold and Headache Maximum Strength Fast Dissolve

NDC 0280-8270 · Bayer HealthCare LLC.

Generic nameaspirin, chlorpheniramine maleate, phenylephrine bitartrate
Dosage formTABLET, EFFERVESCENT
RouteORAL
Active ingredient(s)ASPIRIN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE BITARTRATE
Strength325; 2; 7.8 mg/1; mg/1; mg/1
Pharmacologic classAdrenergic alpha1-Agonists [MoA], Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Decreased Platelet Aggregation [PE], Decreased Prostaglandin Production [PE], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC], Nonsteroidal Anti-inflammatory Drug [EPC], Platelet Aggregation Inhibitor [EPC], alpha-1 Adrenergic Agonist [EPC]
Marketing categoryOTC MONOGRAPH DRUG

Packages

0280-8270-16 — 8 POUCH in 1 CARTON (0280-8270-16) / 2 TABLET, EFFERVESCENT in 1 POUCH

0280-8270-24 — 12 POUCH in 1 CARTON (0280-8270-24) / 2 TABLET, EFFERVESCENT in 1 POUCH

0280-8270-48 — 24 POUCH in 1 CARTON (0280-8270-48) / 2 TABLET, EFFERVESCENT in 1 POUCH

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

0280-2150 — Aspirin,Caffeine, 0280-4000 — ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATE, 0280-8251 — Alka-Seltzer Pain Relief, 0280-8257 — Aspirin/Caffeine Oral Powder, 0280-8260 — ANHYDROUS CITRIC ACID, ASPIRIN, 0280-8265 — aspirin, chlorpheniramine maleate, dextromethorphan hydrobromide, phenylephrine bitartrate, 0280-8266 — aspirin, chlorpheniramine maleate, phenylephrine bitartrate, 0280-8267 — aspirin, chlorpheniramine maleate, dextromethorphan hydrobromide, phenylephrine bitartrate, 0280-8268 — chlorpheniramine maleate, acetaminophen, phenylephrine hydrochloride, dextromethorphan hydrobromide, 0280-8269 — chlorpheniramine maleate, acetaminophen, dextromethorphan hydrobromide, 0280-8271 — chlorpheniramine maleate, acetaminophen, phenylephrine hydrochloride, dextromethorphan hydrobromide, 0280-8274 — chlorpheniramine maleate, dextromethorphan hydrobromide, acetaminophen, phenylephrine hydrochloride, 0280-8280 — chlorpheniramine maleate, acetaminophen, dextromethorphan hydrobromide, 0363-0034 — Acetaminophen, Chlorpheniramine maleate, Dextromethorphan hydrobromide, Phenylephrine hydrochloride, 0363-0157 — Aspirin, 0363-0218 — Aspirin, 0363-0227 — Aspirin, 0363-0374 — Acetaminophen, Aspirin, Caffeine, 0363-0421 — Aspirin, Citric Acid, Sodium Bicarbonate, 0363-0541 — Aspirin, Citric Acid, Sodium Bicarbonate, +960 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels