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Maximum Strength Severe Congestion and Cough

NDC 21130-738 · SAFEWAY

Generic nameDextromethorphan HBr, Guaifenesin, and Phenylephrine HCl
Dosage formLIQUID
RouteORAL
Active ingredient(s)DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, PHENYLEPHRINE HYDROCHLORIDE
Strength20; 400; 10 mg/20mL; mg/20mL; mg/20mL
Pharmacologic classAdrenergic alpha1-Agonists [MoA], Decreased Respiratory Secretion Viscosity [PE], Expectorant [EPC], Increased Respiratory Secretions [PE], Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA], alpha-1 Adrenergic Agonist [EPC]
Marketing categoryOTC MONOGRAPH DRUG

Packages

21130-738-06 — 180 mL in 1 BOTTLE, PLASTIC (21130-738-06)

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

21130-598 — Acetaminophen, Dextromethorphan Hydrobromide, Phenylephrine Hydrochloride, 21130-603 — Acetaminophen, Dextromethorphan Hydrobromide, Doxylamine Succinate, 21130-615 — Acetaminophen, Guaifenesin, Phenylephrine HCl, 21130-627 — Acetaminophen, Guaifenesin, Phenylephrine HCl, 21130-628 — cocoa butter, phenylephrine HCl, 21130-650 — Acetaminophen, Dextromethorphan Hydrobromide, Phenylephrine Hydrochloride, 21130-687 — mineral oil, petrolatum, phenylephrine hydrochloride, 21130-689 — chlorpheniramine maleate, dextromethorphan HBr, 21130-707 — Dextromethorphan HBr, Guaifenesin, 21130-728 — Phenylephrine hydrochloride, 21130-789 — Mineral oil, Petrolatum, and Phenylephrine HCI, 21130-849 — ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, 21130-866 — Acetaminophen, Dextromethorphan Hydrobromide, Phenylephrine Hydrochloride, 21130-890 — Dextromethorphan polistirex, 21130-899 — Acetaminophen, Dextromethorphan HBr, Doxylamine Succinate, 21130-900 — Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl, 21130-907 — acetaminophen, dextromethorphan hydrobromide, and doxylamine succinate, 21130-909 — Acetaminophen 650 mg, Dextromethorphan HBr 20 mg, Guaifenesin 400 mg, Phenylephrine HCl 10 mg, 21130-940 — Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, 21130-947 — Acetaminophen, Dextromethorphan Hydrobromide, Phenylephrine HCl, +3082 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.