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Pain Relief PM

NDC 42507-095 · HYVEE INC

Generic nameAcetaminophen and Diphenhydramine Hydrochloride
Dosage formTABLET, COATED
RouteORAL
Active ingredient(s)ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE
Strength500; 25 mg/1; mg/1
Pharmacologic classHistamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
Marketing categoryOTC MONOGRAPH DRUG

Packages

42507-095-03 — 1 BOTTLE, PLASTIC in 1 CARTON (42507-095-03) / 100 TABLET, COATED in 1 BOTTLE, PLASTIC

42507-095-17 — 225 TABLET, COATED in 1 BOTTLE, PLASTIC (42507-095-17)

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

41520-956 — Acetaminophen, Diphenhydramine HCl, 41520-984 — acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride, 41520-985 — acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride, 41520-996 — DIPHENHYDRAMINE HYDROCHLORIDE, 42291-181 — Butalbital, Acetaminophen, and Caffeine, 42364-0011 — acetaminophen, aspirin, and caffeine, 42364-2208 — acetaminophen, aspirin, and caffeine, 42507-001 — Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, 42507-020 — Acetaminophen, dextromethorphan HBr, doxylamine succinate, phenylephrine HCl, 42507-056 — Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, 42507-103 — Acetaminophen, 42507-148 — Acetaminophen, 42507-163 — ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE, 42507-170 — Acetaminophen, 42507-173 — ACETAMINOPHEN, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE, 42507-205 — Acetaminophen, 42507-219 — ACETAMINOPHEN, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE, 42507-223 — ACETAMINOPHEN and PHENYLEPHRINE HYDROCHLORIDE, 42507-278 — ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE, 42507-290 — DIPHENHYDRAMINE HYDROCHLORIDE, +4329 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels