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POLY-HIST DM

NDC 50991-271 · POLY PHARMACEUTICALS, INC.

Generic nameDEXCHLORPHENIRAMINE MALEATE AND DEXTROMETHORPHAN HBR
Dosage formLIQUID
RouteORAL
Active ingredient(s)DEXTROMETHORPHAN HYDROBROMIDE, DEXCHLORPHENIRAMINE MALEATE
Strength1; 10 mg/5mL; mg/5mL
Pharmacologic classSigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA]
Marketing categoryOTC MONOGRAPH DRUG

Packages

50991-271-15 — 15 mL in 1 BOTTLE (50991-271-15)

50991-271-16 — 473 mL in 1 BOTTLE (50991-271-16)

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

50844-251 — Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl, 50844-252 — Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, 50844-633 — Dextromethorphan HBr and Guaifenesin, 50844-640 — Acetaminophen, Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl, 50844-677 — Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, Phenylephrine HCl, 50844-689 — Chlorpheniramine maleate, Dextromethorphan HBr, 50991-132 — Dextromethorphan HBr, Phenylephrine HCl, Pyrilamine Maleate, 50991-136 — Triprolidine HCl, Dextromethorphan HBr, 50991-142 — Dexbrompheniramine Maleate, Dextromethorphan Hydrobromide and Pseudoephedrine Hydrochloride, 50991-214 — Dextromethorphan HBr, Guaifenesin and Pseudoephedrine HCl, 50991-444 — Dextromethorphan HBr, Pheniramine Maleate, Phenylephrine HCl, 50991-535 — ACETAMINOPHEN, DEXTROMETHORPHAN HBr, GUAIFENESIN, PSEUDOEPHEDRINE HCl, 50991-740 — Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride, 51013-169 — Acetaminophen, Dextromethorphan hydrobromide , Doxylamine succinate, Phenylephrine hydrochloride, 51013-174 — acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride, 51013-175 — Acetaminophen, Phenylephrine hydrochloride, Doxylamine succinate, Dextromethorphan hydrobromide, 51013-666 — ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, 51013-667 — ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, 51013-668 — acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, 51316-009 — Guaifenesin and Dextromethorphan HBR, +1972 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels